23S rRNK (citozin1962-C5)-metiltransferaza
| 23S rRNK (citozin1962-C5)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.191 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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23S rRNK (citozin1962-C5)-metiltransferaza (EC 2.1.1.191, RlmI, metiltransferaza I velike podjedinice rRNK, YccW) je enzim sa sistematskim imenom S-adenozil-L-metionin:23S rRNK (citozin1962-C5)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + citozin1962 u 23S rRNK S-adenozil-L-homocistein + 5-metilcitozin1962 u 23S rRNK
Ovaj enzim specifično metiliše citozin1962 u C5 poziciji 23S rRNK.
Reference[уреди | уреди извор]
- ^ Purta, E., O'Connor, M., Bujnicki, J.M. and Douthwaite, S. (2008). „YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962”. J. Mol. Biol. 383: 641—651. PMID 18786544.
- ^ Sunita, S., Tkaczuk, K.L., Purta, E., Kasprzak, J.M., Douthwaite, S., Bujnicki, J.M. and Sivaraman, J. (2008). „Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes”. J. Mol. Biol. 383: 652—666. PMID 18789337.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 23S+rRNA+(cytosine1962-C5)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
