3-dezoksi-D-mano-oktulozonska kiselina kinaza
Изглед
3-dezoksi-D-mano-oktulozonska kiselina kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.1.166 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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3-dezoksi-D-mano-oktulozonska kiselina kinaza (EC 2.7.1.166, kdkA (gen), Kdo kinaza) je enzim sa sistematskim imenom ATP:(KDO)-lipid IVA 3-dezoksi-alfa-D-mano-okt-2-ulopiranoza 4-fosfotransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim fosforiliše 4-OH poziciju KDO jedinice u (KDO)-lipidu IVA.
Reference[уреди | уреди извор]
- ^ Brabetz, W., Muller-Loennies, S. and Brade, H. (2000). „3-Deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase (WaaA) and kdo kinase (KdkA) of Haemophilus influenzae are both required to complement a waaA knockout mutation of Escherichia coli”. J. Biol. Chem. 275: 34954—34962. PMID 10952982.
- ^ Harper, M., Boyce, J.D., Cox, A.D., St Michael, F., Wilkie, I.W., Blackall, P.J. and Adler, B. (2007). „Pasteurella multocida expresses two lipopolysaccharide glycoforms simultaneously, but only a single form is required for virulence: identification of two acceptor-specific heptosyl I transferases”. Infect. Immun. 75: 3885—3893. PMID 17517879.
- ^ White, K.A., Kaltashov, I.A., Cotter, R.J. and Raetz, C.R. (1997). „A mono-functional 3-deoxy-D-manno-octulosonic acid (Kdo) transferase and a Kdo kinase in extracts of Haemophilus influenzae”. J. Biol. Chem. 272: 16555—16563. PMID 9195966.
- ^ White, K.A., Lin, S., Cotter, R.J. and Raetz, C.R. (1999). „A Haemophilus influenzae gene that encodes a membrane bound 3-deoxy-D-manno-octulosonic acid (Kdo) kinase. Possible involvement of kdo phosphorylation in bacterial virulence”. J. Biol. Chem. 274: 31391—31400. PMID 10531340.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- 3-deoxy-D-manno-octulosonic+acid+kinase на US National Library of Medicine Medical Subject Headings (MeSH)