Demetilsferoiden O-metiltransferaza
| Demetilsferoiden O-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.210 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Demetilsferoiden O-metiltransferaza (EC 2.1.1.210, 1-hidroksikarotenoidna O-metilaza, 1-hidroksikarotenoidna metilaza, 1-HO-karotenoidna metilaza, CrtF) je enzim sa sistematskim imenom S-adenozil-L-metionin:demetilsferoiden O-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + demetilsferoiden S-adenozil-L-homocistein + sferoiden
Kod Rhodopseudomonas capsulata i Rubrivivax gelatinosus ovaj enzim učestvuje u biosintezi sferoidena. Kod Rubrivivax gelatinosus on takođe katalizuje metilaciju demetilspiriloksantina do spiriloksantin, i metilaciju 3,4-didehidrorodopina do anhidrorodovibrina.
Reference[уреди | уреди извор]
- ^ Badenhop, F., Steiger, S., Sandmann, M. and Sandmann, G. (2003). „Expression and biochemical characterization of the 1-HO-carotenoid methylase CrtF from Rhodobacter capsulatus”. FEMS Microbiol. Lett. 222: 237—242. PMID 12770713.
- ^ Pinta, V., Ouchane, S., Picaud, M., Takaichi, S., Astier, C. and Reiss-Husson, F. (2003). „Characterization of unusual hydroxy- and ketocarotenoids in Rubrivivax gelatinosus: involvement of enzyme CrtF or CrtA”. Arch. Microbiol. 179: 354—362. PMID 12664193.
- ^ Scolnik, P.A., Walker, M.A. and Marrs, B.L. (1980). „Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata”. J. Biol. Chem. 255: 2427—2432. PMID 7358679.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Demethylspheroidene+O-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
