Geraniol 8-hidroksilaza
| Geraniol 8-hidroksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.152 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Geraniol 8-hidroksilaza (EC 1.14.13.152, CYP76B6, G10H, CrG10H, SmG10H) je enzim sa sistematskim imenom geraniol,NADPH:kiseonik oksidoreduktaza (8-hidroksilacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- geraniol + NADPH + H+ + O2 (6E)-8-hidroksigeraniol + NADP+ + H2O
Ovaj enzim koristi citohrom P-450. On takođe deluje na nerol i citronelol.
Reference[уреди | уреди извор]
- ^ Collu, G., Unver, N., Peltenburg-Looman, A.M., van der Heijden, R., Verpoorte, R. and Memelink, J. (2001). „Geraniol 10-hydroxylase, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis”. FEBS Lett. 508: 215—220. PMID 11718718.
- ^ Wang, J., Liu, Y., Cai, Y., Zhang, F., Xia, G. and Xiang, F. (2010). „Cloning and functional analysis of geraniol 10-hydroxylase, a cytochrome P450 from Swertia mussotii Franch”. Biosci. Biotechnol. Biochem. 74: 1583—1590. PMID 20699579.
- ^ Sung, P.H., Huang, F.C., Do, Y.Y. and Huang, P.L. (2011). „Functional expression of geraniol 10-hydroxylase reveals its dual function in the biosynthesis of terpenoid and phenylpropanoid”. J. Agric. Food Chem. 59: 4637—4643. PMID 21504162.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Geraniol+8-hydroxylase на US National Library of Medicine Medical Subject Headings (MeSH)
