Glutamil-tRNK reduktaza
| Glutamil-tRNK reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.2.1.70 | ||||||||
| CAS broj | 119940-26-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Glutamil-tRNK reduktaza (EC 1.2.1.70, reduktaza glutamil-tRNK) je enzim sa sistematskim imenom L-glutamat-semialdehid:NADP+ oksidoreduktaza (formira L-glutamil-tRNKGlu).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-glutamat 1-semialdehid + NADP+ + tRNAGlu L-glutamil-tRNAGlu + NADPH + H+
Ovaj enzim formira deo puta za biosintezu 5-aminolevulinata iz glutamata, koji je poznat kao C5 put. Njega koriti većina eubakterija, i sve arhebakterije, alge i biljke.
Reference[уреди | уреди извор]
- ^ von Wettstein, D., Gough, S. and Kannangara, C.G. (1995). „Chlorophyll biosynthesis”. Plant Cell. 7: 1039—1057. PMID 12242396.
- ^ Pontoppidan, B. & Kannangara, C.G. (1994). „Purification and partial characterisation of barley glutamyl-tRNAGlu reductase, the enzyme that directs glutamate to chlorophyll biosynthesis”. Eur. J. Biochem. 225: 529—537. PMID 7957167.
- ^ Schauer, S., Chaturvedi, S., Randau, L., Moser, J., Kitabatake, M., Lorenz, S., Verkamp, E., Schubert, W.D., Nakayashiki, T., Murai, M., Wall, K., Thomann, H.-U., Heinz, D.W., Inokuchi, H, Söll, D. and Jahn, D. (2002). „Escherichia coli glutamyl-tRNA reductase. Trapping the thioester intermediate”. J. Biol. Chem. 277: 48657—48663. PMID 12370189.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Glutamyl-tRNA+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
