Hanoklavin-I dehidrogenaza
Изглед
Hanoklavin-I dehidrogenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.1.1.332 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Hanoklavin-I dehidrogenaza (EC 1.1.1.332, easD (gen), fgaDH (gen)) je enzim sa sistematskim imenom hanoklavin-I:NAD+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hanoklavin-I + NAD+ hanoklavin-I aldehid + NADH + H+
Ovaj enzim katalizuje jedan korak u biosintezi ergot alkaloida kod pojedinih gljiva.
Reference[уреди | уреди извор]
- ^ Wallwey, C., Matuschek, M. and Li, S.M. (2010). „Ergot alkaloid biosynthesis in Aspergillus fumigatus: conversion of chanoclavine-I to chanoclavine-I aldehyde catalyzed by a short-chain alcohol dehydrogenase FgaDH”. Arch. Microbiol. 192: 127—134. PMID 20039019.
- ^ Wallwey, C., Heddergott, C., Xie, X., Brakhage, A.A. and Li, S.M. (2012). „Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae”. Microbiology. 158: 1634—1644. PMID 22403186.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Chanoclavine-I+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)