Holesterol 7a-monooksigenaza
| Holesterol 7a-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.17 | ||||||||
| CAS broj | 9037-53-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Holesterol 7a-monooksigenaza (EC 1.14.13.17, holesterolna 7alfa-hidroksilaza, CYP7A1) je enzim sa sistematskim imenom holesterol,NADPH:kiseonik oksidoreduktaza (7alfa-hidroksilacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- holesterol + NADPH + H+ + O2 7alfa-hidroksiholesterol + NADP+ + H}-2O
Reference[уреди | уреди извор]
- ^ Boyd, G.S., Grimwade, A.M. and Lawson, M.E. (1973). „Studies on rat-liver microsomal cholesterol 7α-hydroxylase”. Eur. J. Biochem. 37: 334—340. PMID 4147676.
- ^ Mitton, J.R., Scholan, N.A. and Boyd, G.S. (1971). „The oxidation of cholesterol in rat liver sub-cellular particles. The cholesterol-7α-hydroxylase enzyme system”. Eur. J. Biochem. 20: 569—579. PMID 4397276.
- ^ Ogishima, T., Deguchi, S. and Okuda, K. (1987). „Purification and characterization of cholesterol 7α-hydroxylase from rat liver microsomes”. J. Biol. Chem. 262: 7646—7650. PMID 3584134.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Cholesterol+7alpha-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
