IRNK (guanin-N7-)-metiltransferaza
| iRNK (guanin-N7-)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.56 | ||||||||
| CAS broj | 56941-25-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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iRNK (guanin-N7-)-metiltransferaza (EC 2.1.1.56, informaciona ribonukleatni guanin 7-metiltransferaza, guanin-7-metiltransferaza, informaciona RNK guanin 7-metiltransferaza, S-adenozil-L-metionin:iRNK (guanin-7-N)-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:iRNK (guanin-N7)-metiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + G5'ppp5'R-iRNK S-adenozil-L-homocistein + m7G5'ppp5'R-iRNK
Nukleozid pored terminalnog guanozina može da bude bilo guanozin ili adenozin.
Reference[уреди | уреди извор]
- ^ Ensinger, M.J., Martin, S.A., Paoletti, E. and Moss, B. (1975). „Modification of the 5′-terminus of mRNA by soluble guanylyl and methyl transferases from vaccinia virus”. Proc. Natl. Acad. Sci. USA. 72: 2525—2529. PMID 1058472.
- ^ Groner, Y., Gilbao, E. and Aviv, H. (1978). „Methylation and capping of RNA polymerase II primary transcripts by HeLa nuclear homogenates”. Biochemistry. 17: 977—982. PMID 629955.
- ^ Martin, S.A. & Moss, B. (1975). „Modification of RNA by mRNA guanylyltransferase and mRNA (guanine-7)methyltransferase from vaccinia virions”. J. Biol. Chem. 250: 9330—9335. PMID 1194287.
- ^ Martin, S.A., Paoletti, E. and Moss, B. (1975). „Purification of mRNA guanylyltransferase and mRNA (guanine-7-) methyltransferase from vaccinia virions”. J. Biol. Chem. 250: 9322—9329. PMID 1194286.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- MRNA+(guanine-N7)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
