N-acetilneuraminat 4-O-acetiltransferaza
| N-acetilneuraminat 4-O-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.44 | ||||||||
| CAS broj | 51004-25-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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N-acetilneuraminat 4-O-acetiltransferaza (EC 2.3.1.44, sijalatna O-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:N-acetilneuraminat 4-O-acetiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + N-acetilneuraminat KoA + N-acetil-4-O-acetilneuraminat
Slobodni i glikozidno vezani N-acetil- i N-glikolil- neuraminati mogu da deluju kao O-acetil akceptori.
Reference[уреди | уреди извор]
- ^ Schauer, R. (1970). „Biosynthese von N-Acetyl-O-acetylneuraminsaüren. I. Inkorporation von [14C]Acetate in Schnitte der Unterkieferspeicheldrüse von Rind und Pferd”. Hoppe-Seyler's Z. Physiol. Chem. 351: 595—602. PMID 5446640.
- ^ Schauer, R. (1970). „Biosynthese von N-Acetyl-O-acetylneuraminsaüren. II. Untersuchungen über Substrat und intracelluläre Lokalisation der Acetyl-coenzym A: N-acetylneuraminat-7- and 8-O-acetyltransferase von Rind”. Hoppe-Seyler's Z. Physiol. Chem. 351: 749—758. PMID 5425947.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- N-acetylneuraminate+4-O-acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
