Nikotinat dehidrogenaza (citohrom)
| Nikotinat dehidrogenaza (citohrom) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.17.2.1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Nikotinat dehidrogenaza (citohrom) (EC 1.17.2.1, nikotinsko kiselinska hidroksilaza, nikotinatna hidroksilaza) je enzim sa sistematskim imenom nikotinat:citohrom 6-oksidoreduktaza (hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- nikotinat + fericitohrom + H2O 6-hidroksinikotinat + ferocitohrom + 2 H+
Ovaj dvokomponentni enzim iz Pseudomonas pripada familiji ksantinskih dehidrogenaza.
Reference[уреди | уреди извор]
- ^ Jimenez, J.I., Canales, A., Jimenez-Barbero, J., Ginalski, K., Rychlewski, L., Garcia, J.L. and Diaz, E. (2008). „Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440”. Proc. Natl. Acad. Sci. USA. 105: 11329—11334. PMID 18678916.
- ^ Yang, Y., Yuan, S., Chen, T., Ma, P., Shang, G. and Dai, Y. (2009). „Cloning, heterologous expression, and functional characterization of the nicotinate dehydrogenase gene from Pseudomonas putida KT2440”. Biodegradation. 20: 541—549. PMID 19118407.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Nicotinate+dehydrogenase+(cytochrome) на US National Library of Medicine Medical Subject Headings (MeSH)
