Nitroalkan oksidaza
| Nitroalkan oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.7.3.1 | ||||||||
| CAS broj | 65802-82-6&title= 9029-36-1, 65802-82-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Nitroalkan oksidaza (EC 1.7.3.1, nitroetanska oksidaza, NAO, nitroetan:kiseonik oksidoreduktaza) je enzim sa sistematskim imenom nitroalkan:kiseonik oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
Za rad ovog enzima je neophodan FAD. Nitroetan je fiziološki supstrat. On takođe deluje na nekoliko drugih nitroalkana, uključujući 1-nitropropan, 2-nitropropan, 1-nitrobutan, 1-nitropentan, 1-nitroheksan, nitrocikloheksan i neke nitroalkanole.
Reference[уреди | уреди извор]
- ^ Little, H.N. (1951). „Oxidation of nitroethane by extracts from Neurospora”. J. Biol. Chem. 193: 347—358. PMID 14907722.
- ^ Kido, T., Hashizume, K. and Soda, K. (1978). „Purification and properties of nitroalkane oxidase from Fusarium oxysporum”. J. Bacteriol. 133: 53—58. PMID 22538.
- ^ Daubner, S.C., Gadda, G., Valley, M.P. and Fitzpatrick, P.F. (2002). „Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily”. Proc. Natl. Acad. Sci. USA. 99: 2702—2707. PMID 11867731.
- ^ Fitzpatrick, P.F., Orville, A.M., Nagpal, A. and Valley, M.P. (2005). „Nitroalkane oxidase, a carbanion-forming flavoprotein homologous to acyl-CoA dehydrogenase”. Arch. Biochem. Biophys. 433: 157—165. PMID 15581574.
- ^ Valley, M.P., Tichy, S.E. and Fitzpatrick, P.F. (2005). „Establishing the kinetic competency of the cationic imine intermediate in nitroalkane oxidase”. J. Am. Chem. Soc. 127: 2062—2066. PMID 15713081.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Nitroalkane+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)
