TRNKMet citidin acetiltransferaza
| TRNKMet citidin acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.193 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
TRNKMet citidin acetiltransferaza (EC 2.3.1.193, YpfI, TmcA) je enzim sa sistematskim imenom acetil-KoA:(elongator tRNKMet)-citidin34 N4-acetiltransferaza (ATP-hidrolizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- [elongator tRNKMet]-citidin34 + ATP + acetil-KoA KoA + [elongator tRNKMet]-N4-acetilcitidin34 + ADP + fosfat
Ovaj enzim acetiluje pokretnu base C34 u CAU antikodonu elongaciono-specifičnog tRNKMet.
Reference[уреди | уреди извор]
- ^ Ikeuchi, Y., Kitahara, K. and Suzuki, T. (2008). „The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon”. EMBO J. 27: 2194—2203. PMID 18668122.
- ^ Chimnaronk, S., Suzuki, T., Manita, T., Ikeuchi, Y., Yao, M., Suzuki, T. and Tanaka, I. (2009). „RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon”. EMBO J. 28: 1362—1373. PMID 19322199.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- TRNAMet+cytidine+acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
