TRNK (guanin10-N2)-metiltransferaza
| tRNK (guanin10-N2)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.214 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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tRNK (guanin10-N2)-metiltransferaza (EC 2.1.1.214, (m2G10) metiltransferaza, Trm11-Trm112 kompleks) je enzim sa sistematskim imenom S-adenozil-L-metionin:tRNK (guanin10-N2)-metiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + guanin10 u tRNK S-adenozil-L-homocistein + N2-metilguanin10 u tRNK
Za razliku od arhejskog enzima, tRNK (guanin10-N2)-dimetiltransferaze (EC 2.1.1.213), tRNK (guanin10-N2)-metiltransferaza iz kvasca ne katalizuje metilaciju N2-metilguanina10 do N2-dimetilguanina10 u tRNK.
Reference[уреди | уреди извор]
- ^ Purushothaman, S.K., Bujnicki, J.M., Grosjean, H. and Lapeyre, B. (2005). „Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA”. Mol. Cell Biol. 25: 4359—4370. PMID 15899842.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- TRNA+(guanine10-N2)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
