Trans,policis-dekaprenil difosfat sintaza
| Trans,policis-dekaprenil difosfat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.86 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Trans,policis-dekaprenil difosfat sintaza (EC 2.5.1.86, Rv2361c, (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-dekaprenil difosfatna sintaza) je enzim sa sistematskim imenom (2Z,6E)-farnezil-difosfat:izopentenil-difosfat farnezilcistransferaza (dodaje 7 izopentenilnih jedinica).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (2Z,6E)-farnezil difosfat + 7 izopentenil difosfat 7 difosfat + trans,oktacis-dekaprenil difosfat
Ovaj enzim učestvuje u biosintezi dekaprenil fosfata.
Reference[уреди | уреди извор]
- ^ Kaur, D., Brennan, P.J. and Crick, D.C. (2004). „Decaprenyl diphosphate synthesis in Mycobacterium tuberculosis”. J. Bacteriol. 186: 7564—7570. PMID 15516568.
- ^ Wang, W., Dong, C., McNeil, M., Kaur, D., Mahapatra, S., Crick, D.C. and Naismith, J.H. (2008). „The structural basis of chain length control in Rv1086”. J. Mol. Biol. 381: 129—140. PMID 18597781.
- ^ Crick, D.C., Schulbach, M.C., Zink, E.E., Macchia, M., Barontini, S., Besra, G.S. and Brennan, P.J. (2000). „Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis”. J. Bacteriol. 182: 5771—5778. PMID 11004176.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Trans,polycis-decaprenyl+diphosphate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
