Tricetin 3',4',5'-O-trimetiltransferaza
| Tricetin 3',4',5'-O-trimetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.169 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Tricetin 3',4',5'-O-trimetiltransferaza (EC 2.1.1.169, FOMT, TaOMT1, TaCOMT1, TaOMT2) je enzim sa sistematskim imenom S-adenozil-L-metionin:tricetin 3',4',5'-O-trimetiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3 S-adenozil-L-metionin + tricetin 3 S-adenozil-L-homocistein + 3',4',5'-O-trimetiltricetin (sveukupna reakcija)
- (1a) S-adenozil-L-metionin + tricetin S-adenozil-L-homocistein + 3'-O-metiltricetin
- (1b) S-adenozil-L-metionin + 3'-O-metiltricetin S-adenozil-L-homocistein + 3',5'-O-dimetiltricetin
- (1c) S-adenozil-L-metionin + 3',5'-O-dimetiltricetin S-adenozil-L-homocistein + 3',4',5'-O-trimetiltricetin
Enzim iz Triticum aestivum katalizuje sekvencionu O-metilaciju tricetina putem 3'-O-metiltricetina, 3',5'-O-metiltricetina do 3',4',5'-O-trimetiltricetina.
Reference[уреди | уреди извор]
- ^ Kornblatt, J.A., Zhou, J.M. and Ibrahim, R.K. (2008). „Structure-activity relationships of wheat flavone O-methyltransferase: a homodimer of convenience”. FEBS J. 275: 2255—2266. PMID 18397325.
- ^ Zhou, J.M., Gold, N.D., Martin, V.J., Wollenweber, E. and Ibrahim, R.K. (2006). „Sequential O-methylation of tricetin by a single gene product in wheat”. Biochim. Biophys. Acta. 1760: 1115—1124. PMID 16730127.
- ^ Zhou, J.M., Seo, Y.W. and Ibrahim, R.K. (2009). „Biochemical characterization of a putative wheat caffeic acid O-methyltransferase”. Plant Physiol. Biochem. 47: 322—326. PMID 19211254.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Tricetin+3',4',5'-O-trimethyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
