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== Literatura ==
== Literatura ==
{{reflist|2}}
{{reflist|2}}

== Dodatna literatura ==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Shukla SD |title=Platelet-activating factor receptor and signal transduction mechanisms. |journal=FASEB J. |volume=6 |issue= 6 |pages= 2296–301 |year= 1992 |pmid= 1312046 |doi= }}
*{{cite journal | author=Sugimoto T, Tsuchimochi H, McGregor CG, ''et al.'' |title=Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heart. |journal=Biochem. Biophys. Res. Commun. |volume=189 |issue= 2 |pages= 617–24 |year= 1993 |pmid= 1281995 |doi=10.1016/0006-291X(92)92245-S }}
*{{cite journal | author=Seyfried CE, Schweickart VL, Godiska R, Gray PW |title=The human platelet-activating factor receptor gene (PTAFR) contains no introns and maps to chromosome 1. |journal=Genomics |volume=13 |issue= 3 |pages= 832–4 |year= 1992 |pmid= 1322356 |doi=10.1016/0888-7543(92)90162-L }}
*{{cite journal | author=Kunz D, Gerard NP, Gerard C |title=The human leukocyte platelet-activating factor receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog. |journal=J. Biol. Chem. |volume=267 |issue= 13 |pages= 9101–6 |year= 1992 |pmid= 1374385 |doi= }}
*{{cite journal | author=Ye RD, Prossnitz ER, Zou AH, Cochrane CG |title=Characterization of a human cDNA that encodes a functional receptor for platelet activating factor. |journal=Biochem. Biophys. Res. Commun. |volume=180 |issue= 1 |pages= 105–11 |year= 1991 |pmid= 1656963 |doi=10.1016/S0006-291X(05)81261-6 }}
*{{cite journal | author=Nakamura M, Honda Z, Izumi T, ''et al.'' |title=Molecular cloning and expression of platelet-activating factor receptor from human leukocytes. |journal=J. Biol. Chem. |volume=266 |issue= 30 |pages= 20400–5 |year= 1991 |pmid= 1657923 |doi= }}
*{{cite journal | author=Haslam RJ, Williams KA, Davidson MM |title=Receptor-effector coupling in platelets: roles of guanine nucleotides. |journal=Adv. Exp. Med. Biol. |volume=192 |issue= |pages= 265–80 |year= 1986 |pmid= 3010668 |doi= }}
*{{cite journal | author=Valone FH |title=Isolation of a platelet membrane protein which binds the platelet-activating factor 1-0-hexadecyl-2-acetyl-SN-glycero-3-phosphorylcholine. |journal=Immunology |volume=52 |issue= 1 |pages= 169–74 |year= 1984 |pmid= 6325330 |doi= | pmc=1454573 }}
*{{cite journal | author=Cundell DR, Gerard NP, Gerard C, ''et al.'' |title=Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. |journal=Nature |volume=377 |issue= 6548 |pages= 435–8 |year= 1995 |pmid= 7566121 |doi= 10.1038/377435a0 }}
*{{cite journal | author=Izumi T, Kishimoto S, Takano T, ''et al.'' |title=Expression of human platelet-activating factor receptor gene in EoL-1 cells following butyrate-induced differentiation. |journal=Biochem. J. |volume=305 ( Pt 3) |issue= |pages= 829–35 |year= 1995 |pmid= 7848283 |doi= | pmc=1136334 }}
*{{cite journal | author=Bito H, Honda Z, Nakamura M, Shimizu T |title=Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA. |journal=Eur. J. Biochem. |volume=221 |issue= 1 |pages= 211–8 |year= 1994 |pmid= 8168510 |doi=10.1111/j.1432-1033.1994.tb18731.x }}
*{{cite journal | author=Chase PB, Halonen M, Regan JW |title=Cloning of a human platelet-activating factor receptor gene: evidence for an intron in the 5'-untranslated region. |journal=Am. J. Respir. Cell Mol. Biol. |volume=8 |issue= 3 |pages= 240–4 |year= 1993 |pmid= 8383507 |doi= }}
*{{cite journal | author=Mutoh H, Bito H, Minami M, ''et al.'' |title=Two different promoters direct expression of two distinct forms of mRNAs of human platelet-activating factor receptor. |journal=FEBS Lett. |volume=322 |issue= 2 |pages= 129–34 |year= 1993 |pmid= 8387031 |doi=10.1016/0014-5793(93)81552-B }}
*{{cite journal | author=Nakamura M, Honda Z, Matsumoto T, ''et al.'' |title=Isolation and properties of platelet-activating factor receptor cDNAs. |journal=Journal of lipid mediators |volume=6 |issue= 1-3 |pages= 163–8 |year= 1993 |pmid= 8395240 |doi= }}
*{{cite journal | author=Kishimoto S, Shimadzu W, Izumi T, ''et al.'' |title=Regulation by IL-5 of expression of functional platelet-activating factor receptors on human eosinophils. |journal=J. Immunol. |volume=157 |issue= 9 |pages= 4126–32 |year= 1996 |pmid= 8892648 |doi= }}
*{{cite journal | author=Chase PB, Yang JM, Thompson FH, ''et al.'' |title=Regional mapping of the human platelet-activating factor receptor gene (PTAFR) to 1p35→p34.3 by fluorescence in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=72 |issue= 2-3 |pages= 205–7 |year= 1997 |pmid= 8978777 |doi=10.1159/000134190 }}
*{{cite journal | author=Le Gouill C, Parent JL, Rola-Pleszczynski M, Stanková J |title=Role of the Cys90, Cys95 and Cys173 residues in the structure and function of the human platelet-activating factor receptor. |journal=FEBS Lett. |volume=402 |issue= 2-3 |pages= 203–8 |year= 1997 |pmid= 9037196 |doi=10.1016/S0014-5793(96)01531-1 }}
*{{cite journal | author=Ahmed A, Dearn S, Shams M, ''et al.'' |title=Localization, quantification, and activation of platelet-activating factor receptor in human endometrium during the menstrual cycle: PAF stimulates NO, VEGF, and FAKpp125. |journal=FASEB J. |volume=12 |issue= 10 |pages= 831–43 |year= 1998 |pmid= 9657523 |doi= }}
*{{cite journal | author=Cargill M, Altshuler D, Ireland J, ''et al.'' |title=Characterization of single-nucleotide polymorphisms in coding regions of human genes. |journal=Nat. Genet. |volume=22 |issue= 3 |pages= 231–8 |year= 1999 |pmid= 10391209 |doi= 10.1038/10290 }}
}}
{{refend}}

Верзија на датум 10. март 2011. у 17:12

Receptor trombocit aktivirajućeg faktora
Identifikatori
Simboli PTAFR; PAFR
Vanjski ID OMIM: 173393 MGI: 106066 HomoloGene: 20260 IUPHAR: PAF GeneCards: PTAFR Gene
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 5724 19204
Ensembl ENSG00000169403 ENSMUSG00000056529
UniProt P25105 Q62035
RefSeq (mRNA) NM_000952 XM_357441
RefSeq (protein) NP_000943 XP_357441
Lokacija (UCSC) Chr 1:
28.35 - 28.39 Mb		 Chr 4:
131.84 - 131.85 Mb
PubMed pretraga [1] [2]

Receptor trombocit aktivirajućeg faktora je G-protein spregnuti receptor koji vezuje trombocit-aktivirajući faktor.[1][2]

PAF receptor manifestuje strukturne karakteristike gena rodopsinske (MIM 180380) familije i vezuje trombocit-aktivirajući faktor (PAF). PAF je fosfolipid (1-0-alkil-2-acetil-sn-glicero-3-fosforilholin) za koji se smatra da posreduje niz patoloških procesa, kao što su alergija, astma, septički šok, arterijska tromboza, i inflamatorni procesi.[3]

Literatura

  1. ^ Seyfried CE, Schweickart VL, Godiska R, Gray PW (1992). „The human platelet-activating factor receptor gene (PTAFR) contains no introns and maps to chromosome 1”. Genomics. 13 (3): 832—4. PMID 1322356. doi:10.1016/0888-7543(92)90162-L. 
  2. ^ Ishii S, Nagase T, Shimizu T (2002). „Platelet-activating factor receptor”. Prostaglandins Other Lipid Mediat. 68-69: 599—609. PMID 12432946. doi:10.1016/S0090-6980(02)00058-8. 
  3. ^ „Entrez Gene: PTAFR platelet-activating factor receptor”. 

Dodatna literatura

  • Shukla SD (1992). „Platelet-activating factor receptor and signal transduction mechanisms.”. FASEB J. 6 (6): 2296—301. PMID 1312046. 
  • Sugimoto T, Tsuchimochi H, McGregor CG; et al. (1993). „Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heart.”. Biochem. Biophys. Res. Commun. 189 (2): 617—24. PMID 1281995. doi:10.1016/0006-291X(92)92245-S. 
  • Seyfried CE, Schweickart VL, Godiska R, Gray PW (1992). „The human platelet-activating factor receptor gene (PTAFR) contains no introns and maps to chromosome 1.”. Genomics. 13 (3): 832—4. PMID 1322356. doi:10.1016/0888-7543(92)90162-L. 
  • Kunz D, Gerard NP, Gerard C (1992). „The human leukocyte platelet-activating factor receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog.”. J. Biol. Chem. 267 (13): 9101—6. PMID 1374385. 
  • Ye RD, Prossnitz ER, Zou AH, Cochrane CG (1991). „Characterization of a human cDNA that encodes a functional receptor for platelet activating factor.”. Biochem. Biophys. Res. Commun. 180 (1): 105—11. PMID 1656963. doi:10.1016/S0006-291X(05)81261-6. 
  • Nakamura M, Honda Z, Izumi T; et al. (1991). „Molecular cloning and expression of platelet-activating factor receptor from human leukocytes.”. J. Biol. Chem. 266 (30): 20400—5. PMID 1657923. 
  • Haslam RJ, Williams KA, Davidson MM (1986). „Receptor-effector coupling in platelets: roles of guanine nucleotides.”. Adv. Exp. Med. Biol. 192: 265—80. PMID 3010668. 
  • Valone FH (1984). „Isolation of a platelet membrane protein which binds the platelet-activating factor 1-0-hexadecyl-2-acetyl-SN-glycero-3-phosphorylcholine.”. Immunology. 52 (1): 169—74. PMC 1454573 Слободан приступ. PMID 6325330. 
  • Cundell DR, Gerard NP, Gerard C; et al. (1995). „Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor.”. Nature. 377 (6548): 435—8. PMID 7566121. doi:10.1038/377435a0. 
  • Izumi T, Kishimoto S, Takano T; et al. (1995). „Expression of human platelet-activating factor receptor gene in EoL-1 cells following butyrate-induced differentiation.”. Biochem. J. 305 ( Pt 3): 829—35. PMC 1136334 Слободан приступ. PMID 7848283. 
  • Bito H, Honda Z, Nakamura M, Shimizu T (1994). „Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA.”. Eur. J. Biochem. 221 (1): 211—8. PMID 8168510. doi:10.1111/j.1432-1033.1994.tb18731.x. 
  • Chase PB, Halonen M, Regan JW (1993). „Cloning of a human platelet-activating factor receptor gene: evidence for an intron in the 5'-untranslated region.”. Am. J. Respir. Cell Mol. Biol. 8 (3): 240—4. PMID 8383507. 
  • Mutoh H, Bito H, Minami M; et al. (1993). „Two different promoters direct expression of two distinct forms of mRNAs of human platelet-activating factor receptor.”. FEBS Lett. 322 (2): 129—34. PMID 8387031. doi:10.1016/0014-5793(93)81552-B. 
  • Nakamura M, Honda Z, Matsumoto T; et al. (1993). „Isolation and properties of platelet-activating factor receptor cDNAs.”. Journal of lipid mediators. 6 (1-3): 163—8. PMID 8395240. 
  • Kishimoto S, Shimadzu W, Izumi T; et al. (1996). „Regulation by IL-5 of expression of functional platelet-activating factor receptors on human eosinophils.”. J. Immunol. 157 (9): 4126—32. PMID 8892648. 
  • Chase PB, Yang JM, Thompson FH; et al. (1997). „Regional mapping of the human platelet-activating factor receptor gene (PTAFR) to 1p35→p34.3 by fluorescence in situ hybridization.”. Cytogenet. Cell Genet. 72 (2-3): 205—7. PMID 8978777. doi:10.1159/000134190. 
  • Le Gouill C, Parent JL, Rola-Pleszczynski M, Stanková J (1997). „Role of the Cys90, Cys95 and Cys173 residues in the structure and function of the human platelet-activating factor receptor.”. FEBS Lett. 402 (2-3): 203—8. PMID 9037196. doi:10.1016/S0014-5793(96)01531-1. 
  • Ahmed A, Dearn S, Shams M; et al. (1998). „Localization, quantification, and activation of platelet-activating factor receptor in human endometrium during the menstrual cycle: PAF stimulates NO, VEGF, and FAKpp125.”. FASEB J. 12 (10): 831—43. PMID 9657523. 
  • Cargill M, Altshuler D, Ireland J; et al. (1999). „Characterization of single-nucleotide polymorphisms in coding regions of human genes.”. Nat. Genet. 22 (3): 231—8. PMID 10391209. doi:10.1038/10290. 
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