CXCL7 — разлика између измена

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==Literatura==
==Literatura==
{{Reflist|2}}
{{Reflist|2}}

==Dodatna literatura==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Begg GS, Pepper DS, Chesterman CN, Morgan FJ |title=Complete covalent structure of human beta-thromboglobulin. |journal=Biochemistry |volume=17 |issue= 9 |pages= 1739–44 |year= 1978 |pmid= 77677 |doi=10.1021/bi00602a024 }}
*{{cite journal | author=Kaplan KL, Broekman MJ, Chernoff A, ''et al.'' |title=Platelet alpha-granule proteins: studies on release and subcellular localization. |journal=Blood |volume=53 |issue= 4 |pages= 604–18 |year= 1979 |pmid= 426909 |doi= }}
*{{cite journal | author=Tunnacliffe A, Majumdar S, Yan B, Poncz M |title=Genes for beta-thromboglobulin and platelet factor 4 are closely linked and form part of a cluster of related genes on chromosome 4. |journal=Blood |volume=79 |issue= 11 |pages= 2896–900 |year= 1992 |pmid= 1316786 |doi= }}
*{{cite journal | author=Cohen AB, Stevens MD, Miller EJ, ''et al.'' |title=Generation of the neutrophil-activating peptide-2 by cathepsin G and cathepsin G-treated human platelets. |journal=Am. J. Physiol. |volume=263 |issue= 2 Pt 1 |pages= L249–56 |year= 1992 |pmid= 1387511 |doi= }}
*{{cite journal | author=Morris SW, Nelson N, Valentine MB, ''et al.'' |title=Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to chromosome 2q35. |journal=Genomics |volume=14 |issue= 3 |pages= 685–91 |year= 1992 |pmid= 1427896 |doi=10.1016/S0888-7543(05)80169-7 }}
*{{cite journal | author=Majumdar S, Gonder D, Koutsis B, Poncz M |title=Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4. |journal=J. Biol. Chem. |volume=266 |issue= 9 |pages= 5785–9 |year= 1991 |pmid= 1826003 |doi= }}
*{{cite journal | author=Wenger RH, Hameister H, Clemetson KJ |title=Human platelet basic protein/connective tissue activating peptide-III maps in a gene cluster on chromosome 4q12-q13 along with other genes of the beta-thromboglobulin superfamily. |journal=Hum. Genet. |volume=87 |issue= 3 |pages= 367–8 |year= 1991 |pmid= 1830861 |doi=10.1007/BF00200921 }}
*{{cite journal | author=Hjemdahl P, Perneby C, Theodorsson E, ''et al.'' |title=A new assay for beta-thromboglobulin in urine. |journal=Thromb. Res. |volume=64 |issue= 1 |pages= 33–43 |year= 1992 |pmid= 1837963 |doi=10.1016/0049-3848(91)90203-9 }}
*{{cite journal | author=Brandt E, Van Damme J, Flad HD |title=Neutrophils can generate their activator neutrophil-activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-activating peptide III. |journal=Cytokine |volume=3 |issue= 4 |pages= 311–21 |year= 1991 |pmid= 1873479 |doi=10.1016/1043-4666(91)90499-4 }}
*{{cite journal | author=Clark-Lewis I, Moser B, Walz A, ''et al.'' |title=Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide. |journal=Biochemistry |volume=30 |issue= 12 |pages= 3128–35 |year= 1991 |pmid= 2007144 |doi=10.1021/bi00226a021 }}
*{{cite journal | author=Walz A, Baggiolini M |title=Generation of the neutrophil-activating peptide NAP-2 from platelet basic protein or connective tissue-activating peptide III through monocyte proteases. |journal=J. Exp. Med. |volume=171 |issue= 2 |pages= 449–54 |year= 1990 |pmid= 2406364 |doi=10.1084/jem.171.2.449 | pmc=2187709 }}
*{{cite journal | author=Holt JC, Harris ME, Holt AM, ''et al.'' |title=Characterization of human platelet basic protein, a precursor form of low-affinity platelet factor 4 and beta-thromboglobulin. |journal=Biochemistry |volume=25 |issue= 8 |pages= 1988–96 |year= 1986 |pmid= 2423119 |doi=10.1021/bi00356a023 }}
*{{cite journal | author=Walz A, Baggiolini M |title=A novel cleavage product of beta-thromboglobulin formed in cultures of stimulated mononuclear cells activates human neutrophils. |journal=Biochem. Biophys. Res. Commun. |volume=159 |issue= 3 |pages= 969–75 |year= 1989 |pmid= 2522778 |doi=10.1016/0006-291X(89)92203-1 }}
*{{cite journal | author=Wenger RH, Wicki AN, Walz A, ''et al.'' |title=Cloning of cDNA coding for connective tissue activating peptide III from a human platelet-derived lambda gt11 expression library. |journal=Blood |volume=73 |issue= 6 |pages= 1498–503 |year= 1989 |pmid= 2713489 |doi= }}
*{{cite journal | author=Castor CW, Walz DA, Ragsdale CG, ''et al.'' |title=Connective tissue activation. XXXIII. Biologically active cleavage products of CTAP-III from human platelets. |journal=Biochem. Biophys. Res. Commun. |volume=163 |issue= 2 |pages= 1071–8 |year= 1989 |pmid= 2783111 |doi=10.1016/0006-291X(89)92330-9 }}
*{{cite journal | author=Holt JC, Rabellino EM, Gewirtz AM, ''et al.'' |title=Occurrence of platelet basic protein, a precursor of low affinity platelet factor 4 and beta-thromboglobulin, in human platelets and megakaryocytes. |journal=Exp. Hematol. |volume=16 |issue= 4 |pages= 302–6 |year= 1988 |pmid= 2966071 |doi= }}
*{{cite journal | author=Castor CW, Furlong AM, Carter-Su C |title=Connective tissue activation: stimulation of glucose transport by connective tissue activating peptide III. |journal=Biochemistry |volume=24 |issue= 7 |pages= 1762–7 |year= 1985 |pmid= 4005226 |doi=10.1021/bi00328a029 }}
*{{cite journal | author=McLaren KM, Pepper DS |title=Immunological localisation of beta-thromboglobulin and platelet factor 4 in human megakaryocytes and platelets. |journal=J. Clin. Pathol. |volume=35 |issue= 11 |pages= 1227–31 |year= 1983 |pmid= 6183294 |doi=10.1136/jcp.35.11.1227 | pmc=497932 }}
*{{cite journal | author=Castor CW, Miller JW, Walz DA |title=Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=80 |issue= 3 |pages= 765–9 |year= 1983 |pmid= 6572368 |doi=10.1073/pnas.80.3.765 | pmc=393460 }}
*{{cite journal | author=Malkowski MG, Wu JY, Lazar JB, ''et al.'' |title=The crystal structure of recombinant human neutrophil-activating peptide-2 (M6L) at 1.9-A resolution. |journal=J. Biol. Chem. |volume=270 |issue= 13 |pages= 7077–87 |year= 1995 |pmid= 7706245 |doi=10.1074/jbc.270.13.7077 }}
}}
{{refend}}

Верзија на датум 17. јул 2010. у 03:04

Pro-trombocit bazični protein (hemokin (C-X-C motiv) ligand 7)
PDB prikaz baziran na 1f9p​.
Dostupne strukture
1f9p​, 1nap​, 1tvx
Identifikatori
Simboli PPBP; PBP; B-TG1; Beta-TG; CTAP-III; CTAP3; CTAPIII; CXCL7; LA-PF4; LDGF; MDGF; NAP-2; SCYB7; TC1; TC2; TGB; TGB1; THBGB; THBGB1
Vanjski ID OMIM121010 MGI1888712 HomoloGene48122 GeneCards: PPBP Gene
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 5473 57349
Ensembl ENSG00000163736 ENSMUSG00000029372
UniProt P02775 n/a
RefSeq (mRNA) NM_002704 NM_023785
RefSeq (protein) NP_002695 NP_076274
Lokacija (UCSC) Chr 4:
75.07 - 75.07 Mb
Chr 5:
91.84 - 91.85 Mb
PubMed pretraga [1] [2]

CXCL7, hemokin (C-X-C motiv) ligand 7, je ljudski gen[1] koji kodira istoimeni protein. CXCL7 je mali citokin iz CXC hemokin familije. On je izoforma beta-tromboglobulina ili pro-trombocit bazični protein (PPBP).[2]

CXCL7 protein se oslobađa u velikim količinama iz trombocita nakon njihove aktivacije.[3] On stimuliše razne procese uključujući mitogenezu, sintezu ekstracelularnog matriksa, metabolizam glukoze i sintezu plazminogen aktivatora.[4][5]

Literatura

  1. ^ „Entrez Gene: PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)”. 
  2. ^ Hristov M, Zernecke A, Bidzhekov K; et al. (2007). „Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury”. Circ. Res. 100 (4): 590—7. PMID 17272812. doi:10.1161/01.RES.0000259043.42571.68.  Непознати параметар |month= игнорисан (помоћ)
  3. ^ Majumdar S, Gonder D, Koutsis B, Poncz M (1991). „Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4”. J Biol Chem. 266 (9): 5785—9. PMID 1826003. 
  4. ^ Castor C, Miller J, Walz D (1983). „Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor”. Proc Natl Acad Sci USA. 80 (3): 765—9. PMC 393460Слободан приступ. PMID 6572368. doi:10.1073/pnas.80.3.765. 
  5. ^ Castor C, Furlong A, Carter-Su C (1985). „Connective tissue activation: stimulation of glucose transport by connective tissue activating peptide III”. Biochemistry. 24 (7): 1762—7. PMID 4005226. doi:10.1021/bi00328a029. 

Dodatna literatura

  • Begg GS, Pepper DS, Chesterman CN, Morgan FJ (1978). „Complete covalent structure of human beta-thromboglobulin.”. Biochemistry. 17 (9): 1739—44. PMID 77677. doi:10.1021/bi00602a024. 
  • Kaplan KL, Broekman MJ, Chernoff A; et al. (1979). „Platelet alpha-granule proteins: studies on release and subcellular localization.”. Blood. 53 (4): 604—18. PMID 426909. 
  • Tunnacliffe A, Majumdar S, Yan B, Poncz M (1992). „Genes for beta-thromboglobulin and platelet factor 4 are closely linked and form part of a cluster of related genes on chromosome 4.”. Blood. 79 (11): 2896—900. PMID 1316786. 
  • Cohen AB, Stevens MD, Miller EJ; et al. (1992). „Generation of the neutrophil-activating peptide-2 by cathepsin G and cathepsin G-treated human platelets.”. Am. J. Physiol. 263 (2 Pt 1): L249—56. PMID 1387511. 
  • Morris SW, Nelson N, Valentine MB; et al. (1992). „Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to chromosome 2q35.”. Genomics. 14 (3): 685—91. PMID 1427896. doi:10.1016/S0888-7543(05)80169-7. 
  • Majumdar S, Gonder D, Koutsis B, Poncz M (1991). „Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4.”. J. Biol. Chem. 266 (9): 5785—9. PMID 1826003. 
  • Wenger RH, Hameister H, Clemetson KJ (1991). „Human platelet basic protein/connective tissue activating peptide-III maps in a gene cluster on chromosome 4q12-q13 along with other genes of the beta-thromboglobulin superfamily.”. Hum. Genet. 87 (3): 367—8. PMID 1830861. doi:10.1007/BF00200921. 
  • Hjemdahl P, Perneby C, Theodorsson E; et al. (1992). „A new assay for beta-thromboglobulin in urine.”. Thromb. Res. 64 (1): 33—43. PMID 1837963. doi:10.1016/0049-3848(91)90203-9. 
  • Brandt E, Van Damme J, Flad HD (1991). „Neutrophils can generate their activator neutrophil-activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-activating peptide III.”. Cytokine. 3 (4): 311—21. PMID 1873479. doi:10.1016/1043-4666(91)90499-4. 
  • Clark-Lewis I, Moser B, Walz A; et al. (1991). „Chemical synthesis, purification, and characterization of two inflammatory proteins, neutrophil activating peptide 1 (interleukin-8) and neutrophil activating peptide.”. Biochemistry. 30 (12): 3128—35. PMID 2007144. doi:10.1021/bi00226a021. 
  • Walz A, Baggiolini M (1990). „Generation of the neutrophil-activating peptide NAP-2 from platelet basic protein or connective tissue-activating peptide III through monocyte proteases.”. J. Exp. Med. 171 (2): 449—54. PMC 2187709Слободан приступ. PMID 2406364. doi:10.1084/jem.171.2.449. 
  • Holt JC, Harris ME, Holt AM; et al. (1986). „Characterization of human platelet basic protein, a precursor form of low-affinity platelet factor 4 and beta-thromboglobulin.”. Biochemistry. 25 (8): 1988—96. PMID 2423119. doi:10.1021/bi00356a023. 
  • Walz A, Baggiolini M (1989). „A novel cleavage product of beta-thromboglobulin formed in cultures of stimulated mononuclear cells activates human neutrophils.”. Biochem. Biophys. Res. Commun. 159 (3): 969—75. PMID 2522778. doi:10.1016/0006-291X(89)92203-1. 
  • Wenger RH, Wicki AN, Walz A; et al. (1989). „Cloning of cDNA coding for connective tissue activating peptide III from a human platelet-derived lambda gt11 expression library.”. Blood. 73 (6): 1498—503. PMID 2713489. 
  • Castor CW, Walz DA, Ragsdale CG; et al. (1989). „Connective tissue activation. XXXIII. Biologically active cleavage products of CTAP-III from human platelets.”. Biochem. Biophys. Res. Commun. 163 (2): 1071—8. PMID 2783111. doi:10.1016/0006-291X(89)92330-9. 
  • Holt JC, Rabellino EM, Gewirtz AM; et al. (1988). „Occurrence of platelet basic protein, a precursor of low affinity platelet factor 4 and beta-thromboglobulin, in human platelets and megakaryocytes.”. Exp. Hematol. 16 (4): 302—6. PMID 2966071. 
  • Castor CW, Furlong AM, Carter-Su C (1985). „Connective tissue activation: stimulation of glucose transport by connective tissue activating peptide III.”. Biochemistry. 24 (7): 1762—7. PMID 4005226. doi:10.1021/bi00328a029. 
  • McLaren KM, Pepper DS (1983). „Immunological localisation of beta-thromboglobulin and platelet factor 4 in human megakaryocytes and platelets.”. J. Clin. Pathol. 35 (11): 1227—31. PMC 497932Слободан приступ. PMID 6183294. doi:10.1136/jcp.35.11.1227. 
  • Castor CW, Miller JW, Walz DA (1983). „Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor.”. Proc. Natl. Acad. Sci. U.S.A. 80 (3): 765—9. PMC 393460Слободан приступ. PMID 6572368. doi:10.1073/pnas.80.3.765. 
  • Malkowski MG, Wu JY, Lazar JB; et al. (1995). „The crystal structure of recombinant human neutrophil-activating peptide-2 (M6L) at 1.9-A resolution.”. J. Biol. Chem. 270 (13): 7077—87. PMID 7706245. doi:10.1074/jbc.270.13.7077.