Линолеат 11-липоксигеназа
| Linoleat 11-lipoksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.45 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Linoleat 11-lipoksigenaza (EC 1.13.11.45, linoleatna dioksigenaza, manganska lipoksigenaza) je enzim sa sistematskim imenom linoleat:kiseonik 11S-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- linoleat + O2 (9Z,12Z)-(11S)-11-hidroperoksioktadeka-9,12-dienoat
Produkt (9Z,12Z)-(11S)-11-hidroperoksioktadeka-9,12-dienoat, se konvertuje u (9Z,11E)-(13R)-13-hidroperoksioktadeka-9,11-dienoat.
Reference[уреди | уреди извор]
- ^ Hamberg, M., Su, C. and Oliw, E.H. (1998). „Manganese lipoxygenase: Discovery of bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction”. J. Biol. Chem. 273: 13080—13088. PMID 9582346.
- ^ Oliw, E.H., Su, C., Skogstrom, T. and Benthin, G. (1998). „Analysis of novel hydroperoxides and other metabolites of oleic, linoleic and linolenic acids by liquid chromatography-mass spectrometry with ion trap MSn”. Lipids. 33: 843—852. PMID 9778131.
- ^ Su, C. & Oliw, E.H. (1998). „Manganese lipoxygenase: Purification and characterization”. J. Biol. Chem. 273: 13072—13079. PMID 9582345.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Linoleate+11-lipoxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
