Citrat lijazna deacetilaza
| Citrat lijazna deacetilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.2.16 | ||||||||
| CAS broj | 58319-93-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Citrat lijazna deacetilaza (EC 3.1.2.16, (citrat-(pro-3S)-lijaza) tiolesteraza, acetil-S-(acil-nosilac protein) enzim tioestarska hidrolaza) je enzim sa sistematskim imenom (citrat-(pro-3S)-lijaza)(acetil-form) hidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- [citrat (pro-3S)-lijaza](acetil form) + 6H2O [citrat (pro-3S)-lijaza](tiol form) + 6 acetat
U proteobakteriji Rubrivivax gelatinosus, ovaj enzim moduliše aktivnost enzima EC 4.1.3.6, citrat (pro-3S)-lijaze, putem njegovog konvertovanja iz aktivne acetil forme u neaktivnu tiolnu formu uklanjanjem acetil grupa.
Reference[уреди | уреди извор]
- ^ Giffhorn, F. & Gottschalk, G. (1975). „Inactivation of citrate lyase from Rhodopseudomonas gelatinosa by a specific deacetylase and inhibition of this inactivation by L-(+)-glutamate”. J. Bacteriol. 124: 1052—1061. PMID 356.
- ^ Giffhorn, F., Rode, H., Kuhn, A. and Gottschalk, G. (1980). „Citrate lyase deacetylase of Rhodopseudomonas gelatinosa. Isolation of the enzyme and studies on the inhibition by L-glutamate”. Eur. J. Biochem. 111: 461—471. PMID 7460909.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Citrate-lyase+deacetylase на US National Library of Medicine Medical Subject Headings (MeSH)
