Katepsin S
| Katepsin S | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.22.27 | ||||||||
| CAS broj | 71965-46-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Katepsin S (EC 3.4.22.27, Cathepsin S) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Slično dejstvo sa katepsinom L, ali sa znatno manjom aktivnošću na Z-Phe-Arg-NHMec, i većom aktivnošću na Z-Val-Val-Arg- jedinjenjima
Ovaj enzim je lizozomalna cisteinska endopeptidaza.
Reference[уреди | уреди извор]
- ^ Turnšek, T., Kregar, I. and Lebez, D. (1975). „Acid sulphydryl protease from calf lymph nodes”. Biochim. Biophys. Acta. 403: 514—520. PMID 1182153.
- ^ Brömme, D., Steinert, A., Friebe, S., Fittkau, S., Wiederanders, B. and Kirschke, H. (1989). „The specificity of bovine spleen cathepsin S. A comparison with rat liver cathepsins L and B”. Biochem. J. 264: 475—485. PMID 2604727.
- ^ Kirschke, H., Wiederanders, B., Brömme, D. and Rinne, A. (1989). „Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins”. Biochem. J. 264: 467—473. PMID 2690828.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Cathepsin+S на US National Library of Medicine Medical Subject Headings (MeSH)
