Komplementna potkomponenta C1r
| Komplementna potkomponenta C1r | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.41 | ||||||||
| CAS broj | 80295-69-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Komplementna potkomponenta C1r (EC 3.4.21.41, aktivirani komplement C1r, C overbar 1r esteraza, aktivirani komplement C1r) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Selektivno odvajanje Lys(ili Arg)-Ile veza u komplementnoj potkomponenti C1s čime se formira C overbar 1s (EC 3.4.21.42)
Ovaj enzim se aktivira iz proenzima C overbar 1r u plazmi.
Reference[уреди | уреди извор]
- ^ Sim, R.B. (1981). „T'he human complement system serine proteases C1r and C1s and their proenzymes”. Methods Enzymol. 80: 26—42. PMID 6281620.
- ^ Leytus, S.P., Kurachi, K., Sakariassen, K.S. and Davie, E.W. (1986). „Nucleotide sequence of the cDNA coding for human complement C1r”. Biochemistry. 25: 4855—4863. PMID 3021205.
- ^ Müller-Eberhard, H.J. (1988). „Molecular organization and function of the complement system”. Annu. Rev. Biochem. 57: 321—347. PMID 3052276.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Complement+subcomponent+C_overbar_1r_ на US National Library of Medicine Medical Subject Headings (MeSH)
