O-aminofenol oksidaza
| O-aminofenol oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.10.3.4 | ||||||||
| CAS broj | 9013-85-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
O-aminofenol oksidaza (EC 1.10.3.4, izofenoksazinska sintaza, o-aminofenol:O2 oksidoreduktaza, 2-aminofenol:O2 oksidoreduktaza, GriF) je enzim sa sistematskim imenom 2-aminofenol:kiseonik oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2 2-aminofenol + O2 + akceptor 2-aminofenoksazin-3-on + redukovani akceptor + 2H2O (sveukupna reakcija)
- (1a) 2 2-aminofenol + O2 2 6-iminocikloheksa-2,4-dienon + 2H2O
- (1b) 2 6-iminocikloheksa-2,4-dienon + akceptor 2-aminofenoksazin-3-on + redukovani akceptor (spontana reakcija)
Ovaj enzim je flavoprotein.
Reference[уреди | уреди извор]
- ^ Nair, P.M. & Vaidynathan, C.S. (1964). „Isophenoxazine synthase”. Biochim. Biophys. Acta. 81: 507—516. PMID 14170322.
- ^ Nair, P.M. & Vining, L.C. (1965). „Isophenoxazine synthase apoenzyme from Pycnoporus coccineus”. Biochim. Biophys. Acta. 96: 318—327. PMID 14298835.
- ^ Subba Rao, P.V. & Vaidyanathan, C.S. (1967). „Studies on the metabolism of o-aminophenol. Purification and properties of isophenoxazine synthase from Bauhenia monandra”. Arch. Biochem. Biophys. 118: 388—394. PMID 4166439.
- ^ Suzuki, H., Furusho, Y., Higashi, T., Ohnishi, Y. and Horinouchi, S. (2006). „A novel o-aminophenol oxidase responsible for formation of the phenoxazinone chromophore of grixazone”. J. Biol. Chem. 281: 824—833. PMID 16282322.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- O-aminophenol+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)
