Peptidilna glicinamidaza
| Peptidilna glicinamidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.19.2 | ||||||||
| CAS broj | 94047-14-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Peptidilna glicinamidaza (EC 3.4.19.2, karboksiamidaza, peptidilna karboksi-amidaza, peptidilna-aminoacilamidaza, karboksamidopeptidaza, peptidilna aminokiselinska amidna hidrolaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvajanje C-terminalnog glicinamida sa polipeptida
Ovaj enzim inaktiviraju vazopresin i oksitocin putem odvajanja glicinamida.
Reference[уреди | уреди извор]
- ^ Fruhaufová, L., Suska-Brezezinska, E., Barth, T. and Rychlik, I. (1973). „Rat liver enzyme inactivating oxytocin and its deamino-carba analogues”. Coll. Czech. Chem. Commun. 38: 2793—2798.
- ^ Nardacci, N.J., Mukhopadhyay, S. and Campbell, B.J. (1975). „Partial purification and characterization of the antidiuretic hormone in toad bladder”. Biochim. Biophys. Acta. 377: 146—157. PMID 1122284.
- ^ Simmons, W.H. & Walter, R. (1980). „Carboxamidopeptidase: purificaction and characterization of a neurohypophyseal hormone inactivating peptidase from toad skin”. Biochemistry. 19: 39—48. PMID 6766314.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Peptidyl-glycinamidase на US National Library of Medicine Medical Subject Headings (MeSH)
