Neutrofilna kolagenaza
| Neutrofilna kolagenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.34 | ||||||||
| CAS broj | 2593923 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Neutrofilna kolagenaza (EC 3.4.24.34, matrična metaloproteinaza 8, PMNL kolagenaza, MMP-8) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje intestinalnih kolagena u trostruko heliksnom domenu. Za raliku od EC 3.4.24.7, intestinalna kolagenaze, ovaj enzim razlaže tip III kolagena sporije nego tip I
Ovaj enzuim je sličan sa interstinalnom kolagenazom.
Reference[uredi | uredi izvor]
- ^ Hasty, K. (1987). „A., Jeffrey, J. J., Hibbs, M. S. and Welgus, H. G. The collagen substrate specificity of human neutrophil collagenase”. J. Biol. Chem. 262: 10048—10052. PMID 3038863.
- ^ Hasty, K. (1990). „A., Pourmotabbed, T. F., Goldberg, G. I., Thompson, J. P., Spinella, D. G., Stevens, R. M. and Mainardi, C. L. Human Neutrophil Collagenase. A distinct gene product with homology to other matrix metalloproteinases”. J. Biol. Chem. 265: 11421—11424. PMID 2164002.
- ^ Knäuper, V., Krämer, S., Reinke, H. and Tschesche, H. (1990). „Characterization and activation of procollagenase from human polymorphonuclear leucocytes. N-terminal sequence and determination of the proenzyme and various proteolytically activated forms”. Eur. J. Biochem. 189: 295—300. PMID 2159879.
Literatura[uredi | uredi izvor]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[uredi | uredi izvor]
- Neutrophil+collagenase на US National Library of Medicine Medical Subject Headings (MeSH)
