4-Oksalokrotonatna dekarboksilaza
(преусмерено са 4-oksalokrotonat dekarboksilaza)
4-Oksalokrotonatna dekarboksilaza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.1.1.77 | ||||||||
CAS broj | 37325-55-6 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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4-Oksalokrotonatna dekarboksilaza (EC 4.1.1.77, 4-oksalokrotonatna karboksilijaza, cnbF (gen), praD (gen), amnE (gen), nbaG (gen), xylI (gen)) je enzim sa sistematskim imenom (3E)-2-oksoheks-3-endioat karboksilijaza (formira 2-oksopent-4-enoat).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (3E)-2-oksoheks-3-enedioat 2-oksopent-4-enoat + CO2
Ovaj enzim učestvuje u degradaciji fenola, modifikovanih fenola i katehola.
Reference[уреди | уреди извор]
- ^ Shingler, V., Marklund, U., Powlowski, J. (1992). „Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600”. J. Bacteriol. 174: 711—724. PMID 1732207.
- ^ Takenaka, S., Murakami, S., Shinke, R. and Aoki, K. (1998). „Metabolism of 2-aminophenol by Pseudomonas sp. AP-3: modified meta-cleavage pathway”. Arch. Microbiol. 170: 132—137. PMID 9683650.
- ^ Stanley, T.M., Johnson, W.H., Jr., Burks, E.A., Whitman, C.P., Hwang, C.C. and Cook, P.F. (2000). „Expression and stereochemical and isotope effect studies of active 4-oxalocrotonate decarboxylase”. Biochemistry. 39: 718—726. PMID 10651637.
- ^ Wang, S.C., Johnson, W.H., Jr., Czerwinski, R.M., Stamps, S.L. and Whitman, C.P. (2007). „Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactions”. Biochemistry. 46: 11919—11929. PMID 17902707.
- ^ Kasai, D., Fujinami, T., Abe, T., Mase, K., Katayama, Y., Fukuda, M. and Masai, E. (2009). „Uncovering the protocatechuate 2,3-cleavage pathway genes”. J. Bacteriol. 191: 6758—6768. PMID 19717587.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 2-oxo-3-hexenedioate+decarboxylase на US National Library of Medicine Medical Subject Headings (MeSH)