Akvalizin 1
| Akvalizin 1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.111 | ||||||||
| CAS broj | 88747-68-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Akvalizin 1 (EC 3.4.21.111, kaldolizin) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Ovaj enzim manifestuje nisku specifičnost za estre aminokiselina sa malim hidrofobnim ili aromatičnim ostacima u P1 poziciji
Ovaj enzim iz ekstremnog termofila, Thermus aquaticus, je alkalna serinska peptidaza.
Reference[уреди | уреди извор]
- ^ Matsuzawa, H., Tokugawa, K., Hamaoki, M., Mizoguchi, M., Taguchi, H., Terada, I., Kwon, S.T. and Ohta, T. (1988). „Purification and characterization of aqualysin I (a thermophilic alkaline serine protease) produced by Thermus aquaticus YT-1”. Eur. J. Biochem. 171: 441—447. PMID 3162211.
- ^ Tanaka, T., Matsuzawa, H., Kojima, S., Kumagai, I., Miura, K. and Ohta, T. (1998). „P1 specificity of aqualysin I (a subtilisin-type serine protease) from Thermus aquaticus YT-1, using P1-substituted derivatives of Streptomyces subtilisin inhibitor”. Biosci. Biotechnol. Biochem. 62: 2035—2038. PMID 9882104.
- ^ Tanaka, T., Matsuzawa, H. and Ohta, T. (1998). „Substrate specificity of aqualysin I, a bacterial thermophilic alkaline serine protease from Thermus aquaticus YT-1: Comparison with proteinase K, subtilisin BPN′ and subtilisin Carlsberg”. Biosci. Biotechnol. Biochem. 62: 2161—2165.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Aqualysin+1 на US National Library of Medicine Medical Subject Headings (MeSH)
