Ekso-1,4-beta-D-glukozaminidaza
Ekso-1,4-beta-D-glukozaminidaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.2.1.165 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ekso-1,4-beta-D-glukozaminidaza (EC 3.2.1.165, CsxA, GlcNaza, eksohitozanaza, GlmA, ekso-beta-D-glukozaminidaza, hitozan ekso-1,4-beta-D-glukozaminidaza) je enzim sa sistematskim imenom hitozan ekso-(1->4)-beta-D-glukosaminidaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza hitozana ili hitozan oligosaharida čime se sukcesivno odvajaju D-glukozaminski ostataci sa neredukujućeg kraja
Hitozan je parcijalno ili totalno N-deacetilisan hitinski derivat koji je prisutan u ćelijskim zidovima pojedinih fitopatogenih gljiva.
Reference[уреди | уреди извор]
- ^ Nanjo, F., Katsumi, R. and Sakai, K. (1990). „Purification and characterization of an exo-β-D-glucosaminidase, a novel type of enzyme, from Nocardia orientalis”. J. Biol. Chem. 265: 10088—10094. PMID 2351651.
- ^ Nogawa, M., Takahashi, H., Kashiwagi, A., Ohshima, K., Okada, H. and Morikawa, Y. (1998). „Purification and characterization of exo-β-D-glucosaminidase from a cellulolytic fungus, Trichoderma reesei PC-3-7”. Appl. Environ. Microbiol. 64: 890—895. PMID 16349528.
- ^ Fukamizo, T., Fleury, A., Côté, N., Mitsutomi, M. and Brzezinski, R. (2006). „Exo-β-D-glucosaminidase from Amycolatopsis orientalis: catalytic residues, sugar recognition specificity, kinetics, and synergism”. Glycobiology. 16: 1064—1072. PMID 16877749.
- ^ Côté, N., Fleury, A., Dumont-Blanchette, E., Fukamizo, T., Mitsutomi, M. and Brzezinski, R. (2006). „Two exo-β-D-glucosaminidases/exochitosanases from actinomycetes define a new subfamily within family 2 of glycoside hydrolases”. Biochem. J. 394: 675—686. PMID 16316314.
- ^ Ike, M., Isami, K., Tanabe, Y., Nogawa, M., Ogasawara, W., Okada, H. and Morikawa, Y. (2006). „Cloning and heterologous expression of the exo-β-D-glucosaminidase-encoding gene (gls93) from a filamentous fungus, Trichoderma reesei PC-3-7”. Appl. Microbiol. Biotechnol. 72: 687—695. PMID 16636831.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Exo-1,4-beta-D-glucosaminidase на US National Library of Medicine Medical Subject Headings (MeSH)