Makrolid 2'-kinaza
| Makrolid 2'-kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.136 | ||||||||
| CAS broj | 116036-69-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Makrolid 2'-kinaza (EC 2.7.1.136) je enzim sa sistematskim imenom ATP:makrolid 2'-O-fosfotransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + oleandomicin ADP + oleandomicin 2'-O-fosfat
Eritromicin, spiramicin i neki drugi makrolidni antibiotici takođe mogu da deluju kao akceptori.
Reference[уреди | уреди извор]
- ^ O'Hara, K., Kanda, T. and Kono, M. (1988). „Structure of a phosphorylated derivative of oleandomycin, obtained by reaction of oleandomycin with an extract of an erythromycin-resistant strain of Escherichia coli”. J. Antibiot. 41: 823—827. PMID 3042731.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Macrolide+2'-kinase на US National Library of Medicine Medical Subject Headings (MeSH)
