Nitrohinolin-N-oksid reduktaza
| Nitrohinolin-N-oksid reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.7.1.9 | ||||||||
| CAS broj | 37256-35-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Nitrohinolin-N-oksid reduktaza (EC 1.7.1.9, 4-nitrohinolin 1-oksidna reduktaza, 4NQO reduktaza, NAD(P)H2:4-nitrohinolin-N-oksidna oksidoreduktaza) je enzim sa sistematskim imenom 4-(hidroksiamino)hinolin N-oksid:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4-(hidroksiamino)hinolin N-oksid + 2 NAD(P)+ +H2O 4-nitrohinolin N-oksid + 2 NAD(P)H + 2 H+
Reference[уреди | уреди извор]
- ^ Toriyama, N. (1965). „[Metabolism of quinoline derivatives. On the reducing enzyme of 4-nitroquinoline-N-oxide]”. Nichidai Igaku Zasshi. 24: 423—432.
- ^ Stanley, J.S., York, J.L. and Benson, A.M. (1992). „Nitroreductases and glutathione transferases that act on 4-nitroquinoline 1-oxide and their differential induction by butylated hydroxyanisole in mice”. Cancer Res. 52: 58—63. PMID 1370076.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Nitroquinoline-N-oxide+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
