Toluen dioksigenaza
| Toluen dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.12.11 | ||||||||
| CAS broj | 120038-36-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Toluen dioksigenaza (EC 1.14.12.11, toluenska 2,3-dioksigenaza) je enzim sa sistematskim imenom toluen,NADH:kiseonik oksidoreduktaza (1,2-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- toluen + NADH + H+ + O2 (1S,2R)-3-metilcikloheksa-3,5-dien-1,2-diol + NAD+
Ovaj enzim je gvožđe-sumporni flavoprotein (FAD).
Reference[уреди | уреди извор]
- ^ Renganathan, V. (1989). „Possible involvement of toluene-2,3-dioxygenase in defluorination of 3-fluoro-substituted benzenes by toluene-degrading Pseudomonas sp. strain T-12”. Appl. Exp. Microbiol. 55: 330—334. PMID 16347845.
- ^ Subramanian, V., Liu, T.-N., Yeh, W.K. and Gibson, D.T. (1979). „Toluene dioxygenase: purification of an iron-sulfur protein by affinity chromatography”. Biochem. Biophys. Res. Commun. 91: 1131—1139. PMID 526270.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Toluene+dioxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
