Кверцетин 2,3-диоксигеназа
| Kvercetin 2,3-dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 1.13.11.24 | ||||||||
| CAS broj | 9075-67-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Kvercetin 2,3-dioksigenaza (EC 1.13.11.24, kvercetinaza, flavonol 2,4-oksigenaza) je enzim sa sistematskim imenom kvercetin:kiseonik 2,3-oksidoreduktaza (deciklizacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- kvercetin + O2 2-(3,4-dihidroksibenzoiloksi)-4,6-dihidroksibenzoat + CO + H+
Enzim iz Aspergillus sp. je bakarni protein, dok enzim iz Bacillus subtilis sadrži gvožđe.
Reference[уреди | уреди извор]
- ^ Oka, T. & Simpson, F.J. (1971). „Quercetinase, a dioxygenase containing copper”. Biochem. Biophys. Res. Commun. 43: 1—5. PMID 5579942.
- ^ Steiner, R.A., Kalk, K.H. and Dijkstra, B.W. (2002). „Anaerobic enzyme·substrate structures provide insight into the reaction mechanism of the copper-dependent quercetin 2,3-dioxygenase”. Proc. Natl. Acad. Sci. USA. 99: 16625—16630. PMID 12486225.
- ^ Bowater, L., Fairhurst, S.A., Just, V.J. and Bornemann, S. (2004). „Bacillus subtilis YxaG is a novel Fe-containing quercetin 2,3-dioxygenase”. FEBS Lett. 557: 45—48. PMID 14741339.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Quercetin+2,3-dioxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
