Alanopin dehidrogenaza
| Alanopin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.1.17 | ||||||||
| CAS broj | 71343-07-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Alanopin dehidrogenaza (EC 1.5.1.17, ALPDH, alanopin(mezo-N-(1-karboksietil)-alanin)dehidrogenaza, meso-N-(1-karboksietil)-alanin:NAD+ oksidoreduktaza, alanopin: NAD+ oksidoreduktaza, ADH, alanopin:NAD+ oksidoreduktaza) je enzim sa sistematskim imenom 2,2'-iminodipropanoat:NAD+ oksidoreduktaza (formira L-alanin).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2,2'-iminodipropanoat + NAD+ +H2O L-alanin + piruvat + NADH + H+
Reakcije teče u reverznom smeru. L-alanin se može zameniti L-cisteinom, L-serinom i L-treoninom. Reakcija sa glicinom je veoma spora, cf. EC 1.5.1.22 strombinska dehidrogenaza.
Reference[уреди | уреди извор]
- ^ Dando, P.R. (1981). „Strombine [N-(carboxymethyl)-D-alanine] dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine dehydrogenase from the mussel Mytilus edulis L”. Biochem. Soc. Trans. 9: 297—298.
- ^ Fields, J.H.A., Eng, A.K., Ramsden, W.D., Hochachka, P.W. and Weinstein, B. (1980). „Alanopine and strombine are novel imino acids produced by a dehydrogenase found in the adductor muscle of the oyster, Crassostrea gigas”. Arch. Biochem. Biophys. 201: 110—114. PMID 6156653.
- ^ Fields, J.H.A. & Hochachka, P.W. (1981). „Purification and properties of alanopine dehydrogenase from the adductor muscle of the oyster, Crassostrea gigas (Mollusca, Bivalvia)”. Eur. J. Biochem. 114: 615—621. PMID 7238503.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Alanopine+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
