Prolin dehidrogenaza
| Prolin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Prolin dehidrogenaza tetramer, Bradyrhizobium diazoefficiens | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.5.99.8 | ||||||||
| CAS broj | 9050-70-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Prolin dehidrogenaza (EC 1.5.99.8, L-prolinska dehidrogenaza, L-prolin:(akceptor) oksidoreduktaza) je enzim sa sistematskim imenom L-prolin:akceptor oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-prolin + akceptor (S)-1-pirolidin-5-karboksilat + redukovani akceptor
Ovaj enzim je flavoprotein (FAD). U mnogim organizmima, od bakterija do sisara, prolin se oksiduje do glutamata u dvostepenom procesu koji obuhvata ovaj enzim i EC 1.5.1.12, 1-pirolidin-5-karboksilat dehidrogenazu.
Reference[уреди | уреди извор]
- ^ Scarpulla, R.C. & Sofer, R.L. (1978). „Membrane-bound proline dehydrogenase from Escherichia coli. Solubilization, purification, and characterization”. J. Biol. Chem. 253: 5997—6001. PMID 355248.
- ^ Forlani, G., Scainelli, D. and Nielsen, E. (1997). „Δ1-Pyrroline-5-carboxylate dehydrogenase from cultured cells of potato (purification and properties)”. Plant Physiol. 113: 1413—1418. PMID 12223682.
- ^ Brown, E.D. & Wood, J.M. (1992). „Redesigned purification yields a fully functional PutA protein dimer from Escherichia coli”. J. Biol. Chem. 267: 13086—13092. PMID 1618807.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Proline+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
