Scitalidopepsin-B
| Scitalidopepsin-B | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 3.4.23.32 | ||||||||
| CAS broj | 104781-89-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Scitalidopepsin-B (EC 3.4.23.32, Scytalidium aspartinska proteinaza B, Ganoderma lucidum karboksilna proteinaza, Ganoderma lucidum aspartinska proteinaza, Scytalidium lignicolum aspartinska proteinaza B, SLB) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza proteina sa širokom specifičnošću. Ralaže se Phe24-Phe, ali ne i Leu15-Tyr i Phe25-Tyr u B lancu insulina
Ovaj enzim je jedna od najmanjih aspartičkih endopeptidaza.
Reference[уреди | уреди извор]
- ^ Terashita, T., Oda, K., Kono, M. and Murao, S. (1981). „Streptomyces pepsin inhibitor-insensitive carboxyl proteinase from Lentinus edodes”. Agric. Biol. Chem. 45: 1937—1943.
- ^ Maita, T., Nagata, S., Matsuda, G., Maruta, S., Oda, K., Murao, S. and Tsuru, D. (1984). „Complete amino acid sequence of Scytalidium lignicolum acid protease B”. J. Biochem. (Tokyo). 95: 465—473. PMID 6370989.
- ^ Terashita, T., Oda, K., Kono, M. and Murao, S. (1984). „Streptomyces pepsin inhibitor-insensitive carboxyl proteinase from Ganoderma lucidum”. Agric. Biol. Chem. 48: 1029—1035.
- ^ Kobayashi, H., Kusakabe, I. and Murakami, K. (1985). „Purification and characterization of a pepstatin-insensitive carboxyl proteinase from Polyporus tulipiferae (Irpex lacteus)”. Agric. Biol. Chem. 49: 2393—2397.
- ^ Tsuru, D., Shimada, S., Maruta, S., Yoshimoto, T., Oda, K., Murao, S., Miyata, T. and Iwanaga, S. (1986). „Isolation and amino acid sequence of a peptide containing an epoxide-reactive residue from the thermolysin-digest of Scytalidium lignicolum acid protease B”. J. Biochem. (Tokyo). 99: 1537—1539. PMID 3519605.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Scytalidopepsin+B на US National Library of Medicine Medical Subject Headings (MeSH)
