Acetilsalicilatna deacetilaza
(преусмерено са Acetilsalicilat deacetilaza)
| Acetilsalicilatna deacetilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.55 | ||||||||
| CAS broj | 87348-04-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Acetilsalicilatna deacetilaza (EC 3.1.1.55, aspirinska esteraza, aspirinska esteraza, acetilsalicilno kiselinska esteraza, aspirinska hidrolaza) je enzim sa sistematskim imenom acetilsalicilat O-acetilhidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Aktivnost jetrenog citozolnog enzima je najviša na acetil estrima aril alkohola.
Reference[уреди | уреди извор]
- ^ Ali, B. & Kaur, S. (1983). „Mammalian tissue acetylsalicylic acid esterase(s): identification, distribution and discrimination from other esterases”. J. Pharmacol. Exp. Ther. 226: 589—594. PMID 6875867.
- ^ Kim, D.-H., Yang, Y.-S. and Jakoby, W.B. (1990). „Aspirin hydrolyzing esterases from rat liver cytosol”. Biochem. Pharmacol. 40: 481—487. PMID 2383281.
- ^ White, K.N. & Hope, D.B. (1984). „Partial purification and characterization of a microsomal carboxylesterase specific for salicylate esters from guinea-pig liver”. Biochim. Biophys. Acta. 785: 138—147. PMID 6704404.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Acetylsalicylate+deacetylase на US National Library of Medicine Medical Subject Headings (MeSH)
