Sirohidrohlorna kobaltohelataza
(преусмерено са Anaerobna kobaltna helataza)
| Sirohidrohlorna kobaltohelataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.99.1.3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Sirohidrohlorna kobaltohelataza (EC 4.99.1.3, CbiK, CbiX, CbiXS, anaerobna kobaltna helataza, sirohidrohlorinska kobalt-lijaza) je enzim sa sistematskim imenom kobalt-sirohidrohlorin kobalt-lijaza (formira sirohidrohlorin).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- kobalt-sirohidrohlorin + 2 H+ sirohidrohlorin + CO2+
Ovaj enzim je helataza tipa II.
Reference[уреди | уреди извор]
- ^ Schubert, H.L., Raux, E., Wilson, K.S. and Warren, M.J. (1999). „Common chelatase design in the branched tetrapyrrole pathways of heme and anaerobic cobalamin synthesis”. Biochemistry. 38: 10660—10669. PMID 10451360.
- ^ Brindley, A.A., Raux, E., Leech, H.K., Schubert, H.L. and Warren, M.J. (2003). „A story of chelatase evolution: Identification and characterisation of a small 13-15 kDa 'ancestral' cobaltochelatase (CbiXS) in the Archaea”. J. Biol. Chem. 278: 22388—22395. PMID 12686546.
- ^ Warren, M.J., Raux, E., Schubert, H.L. and Escalante-Semerena, J.C. (2002). „The biosynthesis of adenosylcobalamin (vitamin B12)”. Nat. Prod. Rep. 19: 390—412. PMID 12195810.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Sirohydrochlorin+cobaltochelatase на US National Library of Medicine Medical Subject Headings (MeSH)
