Limulusni faktor grušavanja C
(преусмерено са Limulus faktor grušavanja C)
| Limulusni faktor grušavanja C | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.84 | ||||||||
| CAS broj | 115743-27-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Limulusni faktor grušavanja C (EC 3.4.21.84, faktor C, limulusni faktor C) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Selektivno razlaganje -Arg103-Ser- i -Ile124-Ile- veza u limulusnom faktoru zguršavanja B čime se formira faktor overbar B. Razlaganje -Pro-Arg- veza u sintetičkim supstratima
Ovaj enzim je izolovan iz hemocitnih granula vrsta rakova Limulus i Tachypleus.
Reference[уреди | уреди извор]
- ^ Nakamura, T., Morita, T. and Iwanaga, S. (1986). „Lipopolysaccharide-sensitive serine-protease zymogen (factor C) found in Limulus hemocytes. Isolation and characterization”. Eur. J. Biochem. 154: 511—521. PMID 3512266.
- ^ Muta, T., Miyata, T., Misumi, Y., Tokunaga, F., Nakamura, T., Toh, Y., Ikehara, Y. and Iwanaga, S. (1991). „Limulus factor C. An endotoxin-sensitive serine protease zymogen with a mosaic structure of complement-like, epidermal growth factor-like, and lectin-like domains”. J. Biol. Chem. 266: 6554—6561. PMID 2007602.
- ^ Tokunaga, F., Nakajima, H. and Iwanaga, S. (1991). „Further studies on lipopolysaccharide-sensitive serine protease zymogen (factor C): its isolation from Limulus polyphemus hemocytes and identification as an intracellular zymogen activated by α-chymotrypsin, not by trypsin”. J. Biochem. (Tokyo). 109: 150—157. PMID 2016264.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Limulus+clotting+factor+_overbar_C_ на US National Library of Medicine Medical Subject Headings (MeSH)
