9,12-Октадекадиеноат 8-хидропероксидна 8С-изомераза
| 9,12-Oktadekadienoat 8-hidroperoksidna 8S-izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.4.4.6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
9,12-Oktadekadienoat 8-hidroperoksidna 8S-izomeraza (EC 5.4.4.6, 8-hidroperoksidna izomeraza, (8R,9Z,12Z)-8-hidroperoksi-9,12-oktadekadienoatna mutaza (formira (7S,8S,9Z,12Z)-7,8-dihidroksi-9,12-oktadekadienoat)) je enzim sa sistematskim imenom (8R,9Z,12Z)-8-hidroperoksioktadeka-9,12-dienoat hidroksimutaza (formira (7S,8S,9Z,12Z)-7,8-dihidroksioktadeka-9,12-dienoat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (8R,9Z,12Z)-8-hidroperoksioktadeka-9,12-dienoat (7S,8S,9Z,12Z)-7,8-dihidroksioktadeka-9,12-dienoat
Ovaj enzim sadrži hem.
Reference
[уреди | уреди извор]- ^ Hamberg, M., Zhang, L.-Y., Brodowsky, I.D. and Oliw, E.H. (1994). „Sequential oxygenation of linoleic acid in the fungus Gaeumannomyces graminis: stereochemistry of dioxygenase and hydroperoxide isomerase reactions”. Arch. Biochem. Biophys. 309: 77—80. PMID 8117115.
- ^ Su, C., Sahlin, M. and Oliw, E.H. (1998). „A protein radical and ferryl intermediates are generated by linoleate diol synthase, a ferric hemeprotein with dioxygenase and hydroperoxide isomerase activities”. J. Biol. Chem. 273: 20744—20751. PMID 9694817.
- ^ Su, C. & Oliw, E.H. (1996). „Purification and characterization of linoleate 8-dioxygenase from the fungus Gaeumannomyces graminis as a novel hemoprotein”. J. Biol. Chem. 271: 14112—14118. PMID 8662736.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- 9,12-octadecadienoate+8-hydroperoxide+8S-isomerase на US National Library of Medicine Medical Subject Headings (MeSH)
