Н-ацетилглукозаминска 6-сулфатаза
| N-acetilglukozaminska 6-sulfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.6.14 | ||||||||
| CAS broj | 65666-34-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
N-acetilglukozaminska 6-sulfataza (EC 3.1.6.14, hondroitinsulfataza, O,N-disulfat O-sulfohidrolaza, acetilglukozamin 6-sulfataza, N-acetilglukozamin 6-sulfat sulfataza, acetilglukozamin 6-sulfataza, 2-acetamido-2-dezoksi-D-glukoza 6-sulfat sulfataza) je enzim sa sistematskim imenom N-acetil-D-glukozamin-6-sulfat 6-sulfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza 6-sulfatnih grupa N-acetil-D-glukozamin 6-sulfatnih jedinica heparan sulfata i keratan sulfata
Ovaj enzim može da bude identičan enzimom EC 3.1.6.11, disulfoglukozamin-6-sulfatazom.
Reference[уреди | уреди извор]
- ^ Basner, R., Kresse, H. and von Figura, K. (1979). „N-Acetylglucosamine-6-sulfate sulfatase from human urine”. J. Biol. Chem. 254: 1151—1158. PMID 762121.
- ^ Kresse, H., Fuchs, W., Glössl, J., Holtfrerich, D. and Gilberg, W. (1981). „Liberation of N-acetylglucosamine-6-sulfate by human β-N-acetylhexosaminidase A”. J. Biol. Chem. 256: 12926—12932. PMID 6458607.
- ^ Weissmann, B., Chao, H. and Chow, P. (1980). „A glucosamine O,N-disulfate O-sulfohydrolase with a probable role in mammalian catabolism of heparan sulfate”. Biochem. Biophys. Res. Commun. 97: 827—833. PMID 6451222.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- N-acetylglucosamine-6-sulfatase на US National Library of Medicine Medical Subject Headings (MeSH)
