Diizopropilna fluorofosfataza

S Vikipedije, slobodne enciklopedije
Diizopropilna fluorofosfataza
Identifikatori
EC broj3.1.8.2
CAS broj9032-18-2
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum

Diizopropilna fluorofosfataza (EC 3.1.8.2, DFPaza, tabunaza, somanaza, organofosforno kiselinska anhidrolaza, organofosfat kiselinska anhidraza, OPA anhidraza, diizopropilfosfofluoridaza, dialkilfluorofosfataza, diizopropil fosforofluoridatna hidrolaza, izopropilfosforofluoridaza, diizopropilfluorofosfonatna dehalogenaza) je enzim sa sistematskim imenom diizopropil-fluorofosfat fluorohidrolaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

diizopropil fluorofosfat + H2O diizopropil fosfat + fluorid

Ovaj enzim deluje na fosforne anhidridne veze (poput fosfor-halida i fosfor-cijanida) u organofosfornim jedinjenjima (uključujući 'nervne gasove').

Reference[uredi | uredi izvor]

  1. ^ Augustinsson, K.-B. & Heimburger, G. (1954). „Enzymatic hydrolysis of organophosphorus compounds. I. Occurrence of enzymes hydrolysing dimethyl-amido-ethoxy-phosphoryl cyanide (Tabun)”. Acta Chem. Scand. 8: 753—761. 
  2. ^ Augustinsson, K.-B. & Heimburger, G. (1954). „Enzymatic hydrolysis of organophosphorus compounds. II. Analysis of reaction products in experiments with Tabun and some properties of blood plasma tabunase”. Acta Chem. Scand. 8: 762—767. 
  3. ^ Augustinsson, K.-B. & Heimburger, G. (1954). „Enzymatic hydrolysis of organophosphorus compounds. IV. Specificity studies”. Acta Chem. Scand. 8: 1533—1541. 
  4. ^ Cohen, J.A. & Warringa, M.G.P.J. (1957). „Purification and properties of dialkylfluorophosphatase”. Biochim. Biophys. Acta. 26: 29—39. PMID 13479457. 
  5. ^ Mounter, L.A. (1960). „Enzymic hydrolysis of organophosphorus compounds”. Ur.: Boyer, P.D., Lardy, H.; Myrb; auml; ck, K. The Enzymes. 4 (2nd izd.). New York: Academic Press. str. 541—550. 
  6. ^ Reiner, E., Aldridge, W.N. and Hoskin, C.G., ur. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. str. —. 

Literatura[uredi | uredi izvor]

  • Reiner, E., Aldridge, W.N. and Hoskin, C.G., ur. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. str. —. 
  • Mounter, L.A. (1960). „Enzymic hydrolysis of organophosphorus compounds”. Ur.: Boyer, P.D., Lardy, H.; Myrb; auml; ck, K. The Enzymes. 4 (2nd izd.). New York: Academic Press. str. 541—550. 

Spoljašnje veze[uredi | uredi izvor]