N-acetilgalaktozamin-6-sulfataza

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

N-acetilgalaktozamin-6-sulfataza
N-acetilgalaktozamin-6-sulfataza
Identifikatori
EC broj	3.1.6.4
CAS broj	9025-60-9
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

N-acetilgalaktozamin-6-sulfataza (EC 3.1.6.4, hondroitinska sulfataza, hondroitinaza, galaktoza-6-sulfatna sulfataza, acetilgalaktozamin 6-sulfataza, N-acetilgalaktozamin-6-sulfatna sulfataza, N-acetilgalaktozamin 6-sulfataza) je enzim sa sistematskim imenom N-acetil-D-galaktozamin-6-sulfat 6-sulfohidrolaza.^[1]^[2]^[3]^[4]^[5] Ovaj enzim katalizuje sledeću hemijsku reakciju

hidroliza 6-sulfatnih grupa N-acetil-D-galaktozamin 6-sulfatnih jedinica hondroitin sulfata i D-galaktoza 6-sulfatnih jedinica keratan sulfata

Reference[uredi | uredi izvor]

^ Epstein, E.H. & Leventhal, M.E. (1981). „Steroid sulfatase of human leukocytes and epidermis and the diagnosis of recessive X-linked ichthyosis”. J. Clin. Invest. 67: 1257—1262. PMID 6939689.
^ Glössl, J. & Kresse, H. (1982). „Impaired degradation of keratan sulphate by Morquio A fibroblasts”. Biochem. J. 203: 335—338. PMID 6213226.
^ Lim, C.T. & Horwitz, A.L. (1981). „Purification and properties of human N-acetylgalactosamine-6-sulfate sulfatase”. Biochim. Biophys. Acta. 657: 344—355. PMID 7213753.
^ Sørensen, S.H., Norén, O., Sjöström, H. and Danielsen, E.M. (1982). „Amphiphilic pig intestinal microvillus maltase/glucoamylase. Structure and specificity”. Eur. J. Biochem. 126: 559—568. PMID 6814909.
^ Yutaka, T., Okada, S., Kato, T., Inui, K. and Yabuchi, H. (1982). „Galactose 6-sulfate sulfatase activity in Morquio syndrome”. Clin. Chim. Acta. 122: 169—180. PMID 6809361.

Literatura[uredi | uredi izvor]

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze[uredi | uredi izvor]

N-acetylgalactosamine-6-sulfatase na US National Library of Medicine Medical Subject Headings (MeSH)

[1] Epstein, E.H. & Leventhal, M.E. (1981). „Steroid sulfatase of human leukocytes and epidermis and the diagnosis of recessive X-linked ichthyosis”. J. Clin. Invest. 67: 1257—1262. PMID 6939689.

[2] Glössl, J. & Kresse, H. (1982). „Impaired degradation of keratan sulphate by Morquio A fibroblasts”. Biochem. J. 203: 335—338. PMID 6213226.

[3] Lim, C.T. & Horwitz, A.L. (1981). „Purification and properties of human N-acetylgalactosamine-6-sulfate sulfatase”. Biochim. Biophys. Acta. 657: 344—355. PMID 7213753.

[4] Sørensen, S.H., Norén, O., Sjöström, H. and Danielsen, E.M. (1982). „Amphiphilic pig intestinal microvillus maltase/glucoamylase. Structure and specificity”. Eur. J. Biochem. 126: 559—568. PMID 6814909.

[5] Yutaka, T., Okada, S., Kato, T., Inui, K. and Yabuchi, H. (1982). „Galactose 6-sulfate sulfatase activity in Morquio syndrome”. Clin. Chim. Acta. 122: 169—180. PMID 6809361.

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p r u Enzimi
Teme	Aktivno mesto Alosterna regulacija Mesto vezivanja Katalitički perfektan enzim Koenzim Kofaktor Kooperativnost EC broj Enzimska kataliza Inhibicija enzima Enzimska kinetika Lajnviver—Berkov dijagram Mihaelis—Mentenina kinetika Spisak enzima
Tipovi	EC1 Oksidoreduktaze /spisak EC2 Transferaze /spisak EC3 Hidrolaze /spisak EC4 Lijaze /spisak EC5 Izomeraze /spisak EC6 Ligaze /spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6