N-acetilneuraminat 7-O(ili 9-O)-acetiltransferaza
N-acetilneuraminat 7-O(ili 9-O)-acetiltransferaza | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 2.3.1.45 | ||||||||
CAS broj | 9054-50-6 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
N-acetilneuraminat 7-O(ili 9-O)-acetiltransferaza (EC 2.3.1.45, N-acetilneuraminatna 7(8)-O-acetiltransferaza, sijalatna O-acetiltransferaza, N-acetilneuraminat 7,8-O-acetiltransferaza, acetil-KoA:N-acetilneuraminat-7- ili 8-O-acetiltransferaza, acetil-KoA:N-acetilneuraminat-7- i/ili 8-O-acetiltransferaza, glikoprotein 7(9)-O-acetiltransferaza, acetil-KoA:N-acetilneuraminat-9(7)-O-acetiltransferaza, N-acetilneuraminat O7-(ili O9-)acetiltransferaza, acetil-KoA:N-acetilneuraminat-9(ili 7)-O-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:N-acetilneuraminat 7-O(or 9-O)-acetiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + N-acetilneuraminat KoA + N-acetil-7-O(or 9-O)-acetilneuraminat
Slobodni i glikozidno vezani N-acetil- i N-glikolil- neuraminati mogu da deluju kao O-acetil akceptori.
Reference
[uredi | uredi izvor]- ^ Schauer, R. (1970). „Biosynthese von N-Acetyl-O-acetylneuraminsaüren. I. Inkorporation von [14C]Acetate in Schnitte der Unterkieferspeicheldrüse von Rind und Pferd”. Hoppe-Seyler's Z. Physiol. Chem. 351: 595—602. PMID 5446640.
- ^ Schauer, R. (1970). „Biosynthese von N-Acetyl-O-acetylneuraminsaüren. II. Untersuchungen über Substrat und intracelluläre Lokalisation der Acetyl-coenzym A: N-acetylneuraminat-7- and 8-O-acetyltransferase von Rind”. Hoppe-Seyler's Z. Physiol. Chem. 351: 749—758. PMID 5425947.
Literatura
[uredi | uredi izvor]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
[uredi | uredi izvor]- N-acetylneuraminate+7-O(or+9-O)-acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)