D-sedoheptuloza 7-fosfatna izomeraza
| D-sedoheptuloza 7-fosfatna izomeraza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 5.3.1.28 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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D-sedoheptuloza 7-fosfatna izomeraza (EC 5.3.1.28, sedoheptuloza-7-fosfat izomeraza, fosfoheptoza izomeraza, gmhA (gen), lpcA (gen)) je enzim sa sistematskim imenom D-glicero-D-mano-heptoza 7-fosfat aldoza-ketoza-izomeraza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-sedoheptuloza 7-fosfat D-glicero-D-mano-heptoza 7-fosfat
Kod Gram-negativih bakterija ovaj enzim učestvuje u biosintezi ADP-L-glicero-beta-D-mano-heptoze.
Reference
[уреди | уреди извор]- ^ Kneidinger, B., Marolda, C., Graninger, M., Zamyatina, A., McArthur, F., Kosma, P., Valvano, M.A. and Messner, P. (2002). „Biosynthesis pathway of ADP-L-glycero-β-D-manno-heptose in Escherichia coli”. J. Bacteriol. 184: 363—369. PMID 11751812.
- ^ Kneidinger, B., Graninger, M., Puchberger, M., Kosma, P. and Messner, P. (2001). „Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose”. J. Biol. Chem. 276: 20935—20944. PMID 11279237.
- ^ Valvano, M.A., Messner, P. and Kosma, P. (2002). „Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides”. Microbiology. 148: 1979—1989. PMID 12101286.
- ^ Kim, M.S. & Shin, D.H. (2009). „A preliminary X-ray study of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei”. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65: 1110—1112. PMID 19923728.
- ^ Taylor, P.L., Blakely, K.M., de Leon, G.P., Walker, J.R., McArthur, F., Evdokimova, E., Zhang, K., Valvano, M.A., Wright, G.D. and Junop, M.S. (2008). „Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants”. J. Biol. Chem. 283: 2835—2845. PMID 18056714.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- D-sedoheptulose+7-phosphate+isomerase на US National Library of Medicine Medical Subject Headings (MeSH)
