HslU-HslV peptidaza
| HslU-HslV peptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 HslU-HslV peptidaza dodekamer, E.Coli | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.25.2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
HslU-HslV peptidaza (EC 3.4.25.2, HslUV, HslV-HslU, HslV peptidaza, ATP-zavisna HslV-HslU proteinaza, kazeinolitička proteaza X, kazeinolitička proteinaza X, ClpXP ATP-zavisna proteaza, ClpXP proteaza, ClpXP serinska proteinaza, Escherichia coli ClpXP serinska proteinaza, HslUV proteaza, HslUV proteinaza, HslVU proteaza, HslVU proteinaza, proteaza HslVU, proteinaza HslUV) je enzim.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP-zavisno razlaganje peptidnih veza sa širokom specifičnošću
Ovaj enzim pripada peptidaznoj familiji T1.
Reference[уреди | уреди извор]
- ^ Wang, J., Rho, S.H., Park, H.H. and Eom, S.H. (2005). „Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects”. Acta Crystallogr. D Biol. Crystallogr. 61: 932—941. PMID 15983416.
- ^ Nishii, W. & Takahashi, K. (2003). „Determination of the cleavage sites in SulA, a cell division inhibitor, by the ATP-dependent HslVU protease from Escherichia coli”. FEBS Lett. 553: 351—354. PMID 14572649.
- ^ Ramachandran, R., Hartmann, C., Song, H.K., Huber, R. and Bochtler, M. (2002). „Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY)”. Proc. Natl. Acad. Sci. USA. 99: 7396—7401. PMID 12032294.
- ^ Yoo, S.J., Seol, J.H., Shin, D.H., Rohrwild, M., Kang, M.S., Tanaka, K., Goldberg, A.L. and Chung, C.H. (1996). „Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli”. J. Biol. Chem. 271: 14035—14040. PMID 8662828.
- ^ Yoo, S.J., Seol, J.H., Seong, I.S., Kang, M.S. and Chung, C.H. (1997). „ATP binding, but not its hydrolysis, is required for assembly and proteolytic activity of the HslVU protease in Escherichia coli”. Biochem. Biophys. Res. Commun. 238: 581—585. PMID 9299555.
- ^ Kanemori, M., Nishihara, K., Yanagi, H. and Yura, T. (1997). „Synergistic roles of HslVU and other ATP-dependent proteases in controlling in vivo turnover of σ32 and abnormal proteins in Escherichia coli”. J. Bacteriol. 179: 7219—7225. PMID 9393683.
- ^ Burton, R.E., Baker, T.A. and Sauer, R.T. (2005). „Nucleotide-dependent substrate recognition by the AAA+ HslUV protease”. Nat. Struct. Mol. Biol. 12: 245—251. PMID 15696175.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- HslU---HslV+peptidase на US National Library of Medicine Medical Subject Headings (MeSH)
