Četica prepoznavanja signala
Četica prepoznavanja signala | |||||||||
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Identifikatori | |||||||||
EC broj | 3.6.5.4 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Četica prepoznavanja signala (EC 3.6.5.4) je enzim sa sistematskim imenom GTP fosfohidrolaza (pomoć pri proteinskoj sintezi).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- GTP + H2O GDP + fosfat
Dejstvo ovih enzima je vezano za prepoznavanje signalnih čestica.
Reference[уреди | уреди извор]
- ^ Connolly, T. & Gilmore, R. (1989). „The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide”. Cell. 57: 599—610. PMID 2541918.
- ^ Connolly, T., Rapiejko, P.J. and Gilmore, R. (1991). „Requirement of GTP hydrolysis for dissociation of the signal recognition particle from its receptor”. Science. 252: 1171—1173. PMID 1851576.
- ^ Miller, J.D., Wilhelm, H., Gierasch, L., Gilmore, R. and Walter, P. (1993). „GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation”. Nature. 366: 351—354. PMID 8247130.
- ^ Freymann, D.M., Keenan, R.J., Stroud, R.M. and Walter, P. (1997). „Structure of the conserved GTPase domain of the signal recognition particle”. Nature. 385: 361—364. PMID 9002524.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Signal-recognition-particle+GTPase на US National Library of Medicine Medical Subject Headings (MeSH)