4,4'-diapofitoen desaturaza
| 4,4'-diapofitoen desaturaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.8.2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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4,4'-diapofitoen desaturaza (EC 1.3.8.2, dehidroskvalenska desaturaza, CrtN, 4,4'-diapofitoen:FAD oksidoreduktaza) je enzim sa sistematskim imenom 15-cis-4,4'-diapofitoen:FAD oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 15-cis-4,4'-diapofitoen + 4 FAD sve--trans-4,4'-diapolikopen + 4 FADH2 (sveukupna reakcija)
- (1a) 15-cis-4,4'-diapofitoen + FAD sve-trans-4,4'-diapofitofluen + FADH2
- (1b) sve-trans-4,4'-diapofitofluen + FAD sve-trans-4,4'-diapo-zeta-karoten + FADH2
- (1c) sve-trans-4,4'-diapo-zeta-karoten + FAD sve-trans-4,4'-diaponeurosporen + FADH2
- (1d) sve-trans-4,4'-diaponeurosporen + FAD sve-trans-4,4'-diapolikopen + FADH2
Ovaj enzim je tipičan za Staphylococcus aureus i neke druge bakterije kao što je Heliobacillus sp. On je odgovoran za četiri sukcesivne dehidrogenacije.
Reference[уреди | уреди извор]
- ^ Wieland, B., Feil, C., Gloria-Maercker, E., Thumm, G., Lechner, M., Bravo, J.M., Poralla, K. and Gotz, F. (1994). „Genetic and biochemical analyses of the biosynthesis of the yellow carotenoid 4,4′-diaponeurosporene of Staphylococcus aureus”. J. Bacteriol. 176: 7719—7726. PMID 8002598.
- ^ Raisig, A. & Sandmann, G. (1999). „4,4′-diapophytoene desaturase: catalytic properties of an enzyme from the C30 carotenoid pathway of Staphylococcus aureus”. J. Bacteriol. 181: 6184—6187. PMID 10498735.
- ^ Raisig, A. & Sandmann, G. (2001). „Functional properties of diapophytoene and related desaturases of C30 to C40 carotenoid biosynthetic pathways”. Biochim. Biophys. Acta. 1533: 164—170. PMID 11566453.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 4,4'-diapophytoene+desaturase на US National Library of Medicine Medical Subject Headings (MeSH)
