Acetilajmalinska estaraza
| Acetilajmalinska estaraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.80 | ||||||||
| CAS broj | 110183-46-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Acetilajmalinska estaraza (EC 3.1.1.80, AAE, 2beta(R)-17-O-acetilajmalan:acetilesteraza, acetilajmalanska esteraza) je enzim sa sistematskim imenom 17-O-acetilajmalin O-acetilhidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1) 17-O-acetilajmaline + H2O ajmalin + acetat
- (2) 17-O-acetilnorajmaline + H2O norajmaline + acetat
Ovaj biljni enzim je odgovoran za zadnji stupanj biosinteze indolnog alkaloida ajmalina.
Reference[уреди | уреди извор]
- ^ Polz, L., Schübel, H. and Stöckigt, J. (1987). „Characterization of 2β(R)-17-O-acetylajmalan:acetylesterase—a specific enzyme involved in the biosynthesis of the Rauwolfia alkaloid ajmaline”. Z. Naturforsch. [C]. 42: 333—342. PMID 2955586.
- ^ Ruppert, M., Woll, J., Giritch, A., Genady, E., Ma, X. and Stöckigt, J. (2005). „Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system”. Planta. 222: 888—898. PMID 16133216.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Acetylajmaline+esterase на US National Library of Medicine Medical Subject Headings (MeSH)
