Adenilil-(glutamat—amonijak ligaza) hidrolaza

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Adenilil-(glutamat—amonijak ligaza) hidrolaza
Adenilil-(glutamat—amonijak ligaza) hidrolaza
Identifikatori
EC broj	3.1.4.15
CAS broj	37288-22-5
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Adenilil-(glutamat—amonijak ligaza) hidrolaza (EC 3.1.4.15, adenilil-(glutamin-sintetaza)hidrolaza, adenilil(glutamin sintetaza) hidrolaza) je enzim sa sistematskim imenom adenilil-(L-glutamat:amonijak ligaza (formira ADP)) adenililhidrolaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

adenilil-[L-glutamat:amonijak ligaza (formira ADP)] + H₂O

\rightleftharpoons

adenilat + [L-glutamat:amonijak ligaza (formira ADP)]

Reference[уреди | уреди извор]

^ Heilmeyer, L., Battig, F. and Holzer, H. (1968). „Characterization of a glutamine synthetase b activating (deadenylylating) enzyme system in Escherichia coli”. Eur. J. Biochem. 9: 259—262.
^ Shapiro, B.M. (1969). „The glutamine synthetase deadenylylating enzyme system from Escherichia coli. Resolution into two components, specific nucleotide stimulation, and cofactor requirements”. Biochemistry. 8: 659—659. PMID 4893578.
^ Shapiro, B.M. & Stadtman, E.R. (1968). „5′-Adenylyl-O-tyrosine. The novel phosphodiester residue of adenylylated glutamine synthetase from Escherichia coli”. J. Biol. Chem. 243: 3769—3771. PMID 4298074.

Literatura[уреди | уреди извор]

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze[уреди | уреди извор]

Adenylyl-(glutamate---ammonia+ligase)+hydrolase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Heilmeyer, L., Battig, F. and Holzer, H. (1968). „Characterization of a glutamine synthetase b activating (deadenylylating) enzyme system in Escherichia coli”. Eur. J. Biochem. 9: 259—262.

[2] Shapiro, B.M. (1969). „The glutamine synthetase deadenylylating enzyme system from Escherichia coli. Resolution into two components, specific nucleotide stimulation, and cofactor requirements”. Biochemistry. 8: 659—659. PMID 4893578.

[3] Shapiro, B.M. & Stadtman, E.R. (1968). „5′-Adenylyl-O-tyrosine. The novel phosphodiester residue of adenylylated glutamine synthetase from Escherichia coli”. J. Biol. Chem. 243: 3769—3771. PMID 4298074.

[1]

[2]

[3]

п р у Enzimi
Teme	Aktivno mesto Alosterna regulacija Mesto vezivanja Katalitički perfektan enzim Koenzim Kofaktor Kooperativnost EC broj Enzimska kataliza Inhibicija enzima Enzimska kinetika Lajnviver—Berkov dijagram Mihaelis—Mentenina kinetika Spisak enzima
Tipovi	EC1 Oksidoreduktaze /spisak EC2 Transferaze /spisak EC3 Hidrolaze /spisak EC4 Lijaze /spisak EC5 Izomeraze /spisak EC6 Ligaze /spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6