Albendazol monooksigenaza
| Albendazol monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.32 | ||||||||
| CAS broj | 101299-59-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Albendazol monooksigenaza (EC 1.14.13.32, albendazolna oksidaza, albendazolna sulfoksidaza) je enzim sa sistematskim imenom albendazol,NADPH:kiseonik oksidoreduktaza (formira sulfoksid).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- albendazol + NADPH + H+ + O2 albendazol S-oksid + NADP+ + H2O
Ovaj enzim je flavoprotein (FAD).
Reference[уреди | уреди извор]
- ^ Fargetton, X., Galtier, P. and Delatour, P. (1986). „Sulfoxidation of albendazole by a cytochrome P450-independent monooxygenase from rat liver microsomes”. Vet. Res. Commun. 10: 317—324. PMID 3739217.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Albendazole+monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
