Arilestaraza

С Википедије, слободне енциклопедије
Arilestaraza
Identifikatori
EC broj3.1.1.2
CAS broj9032-73-9
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum

Arilestaraza (EC 3.1.1.2, A-esteraza, paraoksonaza, aromatična esteraza) je enzim sa sistematskim imenom aril-estar hidrolaza.[1][2][3][4][5][6][7][8] Ovaj enzim katalizuje sledeću hemijsku reakciju

fenil acetat + H2O fenol + acetat

Ovaj enzim deluje na mnoge fenolne estre.

Reference[уреди | уреди извор]

  1. ^ Aldridge, W.N. (1953). „Serum esterases. I. Two types of esterase (A and B) hydrolysing p-nitrophenyl acetate, propionate and butyrate and a method for their determination”. Biochem. J. 53: 110—117. PMID 13032041. 
  2. ^ Augustinsson, K.-B. & Olsson, B. (1959). „Esterases in the milk and blood plasma of swine. 1. Substrate specificity and electrophoresis studies”. Biochem. J. 71: 477—484. PMID 13638253. 
  3. ^ Bosmann, H.B. (1972). „Membrane marker enzymes. Characterization of an arylesterase of guinea pig cerebral cortex utilizing p-nitrophenyl acetate as substrate”. Biochim. Biophys. Acta. 276: 180—191. PMID 5047702. 
  4. ^ Kim, D.-H., Yang, Y.-S. and Jakoby, W.B. (1990). „Nonserine esterases from rat liver cytosol”. Protein Expr. Purif. 1: 19—27. PMID 2152179. 
  5. ^ Mackness, M.I., Thompson, H.M., Hardy, A.R. and Walker, C.H. (1987). „Distinction between 'A′-esterases and arylesterases. Implications for esterase classification”. Biochem. J. 245: 293—296. PMID 2822017. 
  6. ^ Reiner, E., Aldridge, W.N. and Hoskin, C.G., ур. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. стр. —. 
  7. ^ Khersonsky, O. & Tawfik, D.S. (2005). „Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase”. Biochemistry. 44: 6371—6382. PMID 15835926. 
  8. ^ Draganov, D.I., Teiber, J.F., Speelman, A., Osawa, Y., Sunahara, R. and La Du, B.N. (2005). „Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities”. J. Lipid Res. 46: 1239—1247. PMID 15772423. 

Литература[уреди | уреди извор]

  • Reiner, E., Aldridge, W.N. and Hoskin, C.G., ур. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. стр. —. 

Spoljašnje veze[уреди | уреди извор]

  • Arylesterase на US National Library of Medicine Medical Subject Headings (MeSH)